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The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
COVID-19 vaccine development: milestones, lessons and prospects
M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
Low neutralization of SARS-CoV-2 Omicron BA. 2.75. 2, BQ. 1.1 and XBB. 1 by parental mRNA vaccine or a BA. 5 bivalent booster
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Omicron sublineages, including the BA. 2-derived BA. 2.75. 2 and the BA. 5-derived BQ. 1.1 …
Omicron sublineages, including the BA. 2-derived BA. 2.75. 2 and the BA. 5-derived BQ. 1.1 …
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in
Botswana and South Africa,–. It has since spread to many countries and is expected to …
Botswana and South Africa,–. It has since spread to many countries and is expected to …
[HTML][HTML] Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study
Background Vaccine effectiveness studies have not differentiated the effect of the delta (B.
1.617. 2) variant and potential waning immunity in observed reductions in effectiveness …
1.617. 2) variant and potential waning immunity in observed reductions in effectiveness …
Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera
A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl… - Science, 2022 - science.org
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …
Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape
Where 2020 saw the development and testing of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has …
syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has …
The emergence, genomic diversity and global spread of SARS-CoV-2
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …
Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review
Background Vaccines are critical cost-effective tools to control the coronavirus disease 2019
(COVID-19) pandemic. However, the emergence of variants of the severe acute respiratory …
(COVID-19) pandemic. However, the emergence of variants of the severe acute respiratory …
Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine through 6 months
Background BNT162b2 is a lipid nanoparticle–formulated, nucleoside-modified RNA
vaccine encoding a prefusion-stabilized, membrane-anchored severe acute respiratory …
vaccine encoding a prefusion-stabilized, membrane-anchored severe acute respiratory …