Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

The phenomenon of ion mobility (IM), the movement/transport of charged particles under the
influence of an electric field, was first observed in the early 20th Century and harnessed later …

Collision cross sections in both helium and nitrogen gases were measured directly using a
drift cell with RF ion confinement inserted within a quadrupole/ion mobility/time-of-flight …

Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …

Traditionally, mass spectrometry has been a powerful analytical method enabling the
structural analysis of small molecules, and later on peptides and proteins. With the advent of …

One difficulty in using ion mobility (IM) mass spectrometry (MS) to improve the specificity of
peptide ion assignments is that IM separations are performed using a range of pressures …

The use of ion mobility separation to determine the collision cross‐section of a gas‐phase
ion can provide valuable structural information. The introduction of travelling‐wave ion …

The technique of ion mobility mass spectrometry (IM-MS) has become of increasing interest
for rapid analysis of the conformations adopted by biological macromolecules. It is currently …

Mass spectrometry-based methods have become increasingly important in structural biology—
in particular for large and dynamic, even heterogeneous assemblies of biomolecules. Native …

Collision cross section (CCS) measurement of lipids using traveling wave ion mobility-mass
spectrometry (TWIM-MS) is of high interest to the lipidomics field. However, currently …