A fundamental goal of research in neuroscience is to uncover the causal structure of the
brain. This focus on causation makes sense, because causal information can provide …

The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …

Catatonia is a psychomotor disorder featuring stupor, posturing, and echophenomena. This
Series paper examines the evidence for immune dysregulation in catatonia. Activation of the …

Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut
microbiota can signal to the brain via the immune system, the vagus nerve or other host …

Historical epidemiological perspectives from past pandemics and recent neurobiological
evidence link infections and psychoses, leading to concerns that COVID-19 will present a …

The notion of immunological pathways playing a role in the etiology of a subset of psychotic
disorders has received increased interest in the last decades. One of the findings that has …

AimsIt has been suggested that people with mental disorders have an elevated risk to
acquire severe acute respiratory syndrome coronavirus 2 and to be disproportionally …

Encephalitis describes inflammation of the brain parenchyma, typically caused by either an
infectious agent or through an autoimmune process which may be postinfectious …

The autoimmune encephalitis (AE) syndromes have been characterised by the detection of
autoantibodies in serum and/or cerebrospinal fluid which target the extracellular domains of …

A causal relationship between immune dysregulation and schizophrenia has been
supported by genome-wide association studies and epidemiological evidence. It remains …