Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future
Neisseria gonorrhoeae is evolving into a superbug with resistance to previously and
currently recommended antimicrobials for treatment of gonorrhea, which is a major public …
currently recommended antimicrobials for treatment of gonorrhea, which is a major public …
Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development
PA Rice, WM Shafer, S Ram… - Annual review of …, 2017 - annualreviews.org
Gonorrhea, an obligate human infection, is on the rise worldwide and gonococcal strains
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation
Sensing of microbes activates the innate immune system, depending on functional
mitochondria. However, pathogenic bacteria inhibit mitochondrial activity by delivering …
mitochondria. However, pathogenic bacteria inhibit mitochondrial activity by delivering …
Immune responses to Neisseria gonorrhoeae and implications for vaccine development
Neisseria gonorrheoae is the causative agent of gonorrhea, a sexually transmitted infection
responsible for a major burden of disease with a high global prevalence. Protective …
responsible for a major burden of disease with a high global prevalence. Protective …
Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding
Multidrug-resistant (MDR) gram-negative bacteria have increased the prevalence of fatal
sepsis in modern times. Colistin is a cationic antimicrobial peptide (CAMP) antibiotic that …
sepsis in modern times. Colistin is a cationic antimicrobial peptide (CAMP) antibiotic that …
[HTML][HTML] The global roadmap for advancing development of vaccines against sexually transmitted infections: update and next steps
SL Gottlieb, CD Deal, B Giersing, H Rees, G Bolan… - Vaccine, 2016 - Elsevier
Abstract In 2014, the World Health Organization, the US National Institutes of Health, and
global technical partners published a comprehensive roadmap for development of new …
global technical partners published a comprehensive roadmap for development of new …
The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae
I Leduc, KL Connolly, A Begum, K Underwood… - PLoS …, 2020 - journals.plos.org
There is a pressing need for a gonorrhea vaccine due to the high disease burden
associated with gonococcal infections globally and the rapid evolution of antibiotic …
associated with gonococcal infections globally and the rapid evolution of antibiotic …
Progress toward a gonococcal vaccine: the way forward
The concept of immunizing against gonorrhea has received renewed interest because of the
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …
Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae
JS Stevens, AK Criss - Current opinion in hematology, 2018 - journals.lww.com
Pathogenesis of Neisseria gonorrhoeae in the female reproduc... : Current Opinion in
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …
Hematology Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract …
Is gonococcal disease preventable? The importance of understanding immunity and pathogenesis in vaccine development
Gonorrhea is a major, global public health problem for which there is no vaccine. The
continuing emergence of antibiotic-resistant strains raises concerns that untreatable …
continuing emergence of antibiotic-resistant strains raises concerns that untreatable …