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Calcium (Ca2+) signaling in plants: A plant stress perspective
Abstract Calcium ions (Ca 2+) serve as ubiquitous signaling molecules and are involved in
diverse biological processes, particularly pivotal in plant growth and stress response. When …
diverse biological processes, particularly pivotal in plant growth and stress response. When …
[HTML][HTML] Organelle homeostasis requires ESCRTs
The endosomal sorting complexes required for transport (ESCRT) catalyze membrane
shape transformations throughout the cell. Canonical functions of the ESCRTs include …
shape transformations throughout the cell. Canonical functions of the ESCRTs include …
Calcium signaling from damaged lysosomes induces cytoprotective stress granules
J Duran, JE Salinas, RP Wheaton, S Poolsup… - The EMBO …, 2024 - embopress.org
Lysosomal damage induces stress granule (SG) formation. However, the importance of SGs
in determining cell fate and the precise mechanisms that mediate SG formation in response …
in determining cell fate and the precise mechanisms that mediate SG formation in response …
Neuronal constitutive endolysosomal perforations enable α-synuclein aggregation by internalized PFFs
Endocytosis, required for the uptake of receptors and their ligands, can also introduce
pathological aggregates such as α-synuclein (α-syn) in Parkinson's Disease. We show here …
pathological aggregates such as α-synuclein (α-syn) in Parkinson's Disease. We show here …
Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca2+-sensor ALG-2
Apoptosis linked Gene-2 (ALG-2) is a multifunctional intracellular Ca2+ sensor and the
archetypal member of the penta-EF hand protein family. ALG-2 functions in the repair of …
archetypal member of the penta-EF hand protein family. ALG-2 functions in the repair of …
Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C
X Wang, P Xu, A Bentley-DeSousa, W Hancock-Cerutti… - bioRxiv, 2024 - biorxiv.org
Based on genetic studies, lysosome dysfunction is thought to play a pathogenetic role in
Parkinson's disease (PD). Here we show that VPS13C, a bridge-like lipid transport protein …
Parkinson's disease (PD). Here we show that VPS13C, a bridge-like lipid transport protein …
A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival
J Duran, S Poolsup, L Allers, MR Lemus, Q Cheng… - …, 2024 - pmc.ncbi.nlm.nih.gov
Lysosomal damage poses a significant threat to cell survival. Our previous work has
reported that lysosomal damage induces stress granule (SG) formation. However, the …
reported that lysosomal damage induces stress granule (SG) formation. However, the …
[HTML][HTML] Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic pathway and is an effector of CASM
MG Hanna, HOR Cruz, K Fujise, Z Li, M Monetti… - …, 2024 - pmc.ncbi.nlm.nih.gov
Recent studies have identified a family of rod-shaped proteins which includes VPS13 and
ATG2 and are thought to mediate unidirectional lipid transport at intracellular membrane …
ATG2 and are thought to mediate unidirectional lipid transport at intracellular membrane …
[PDF][PDF] THESIS/THÈSE
C Delmotte - 2018 - pure.unamur.be
Obesity is associated with white adipose tissue dysfunction leading to obesity-associated
diseases such as chronic kidney disease. In this disease, renal proximal tubular epithelial …
diseases such as chronic kidney disease. In this disease, renal proximal tubular epithelial …