Measuring DNA modifications with the comet assay: a compendium of protocols
A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
Comet assay: a reliable tool for the assessment of DNA damage in different models
A Dhawan, M Bajpayee, D Parmar - Cell biology and toxicology, 2009 - Springer
New chemicals are being added each year to the existing burden of toxic substances in the
environment. This has led to increased pollution of ecosystems as well as deterioration of …
environment. This has led to increased pollution of ecosystems as well as deterioration of …
The Comet assay for the evaluation of genotoxic impact in aquatic environments
G Frenzilli, M Nigro, BP Lyons - Mutation research/reviews in mutation …, 2009 - Elsevier
This review considers the potential of the Comet assay (or Single Cell Gel Electrophoresis,
SCGE) to evaluate the environmental impact of genotoxins in aquatic environments. It …
SCGE) to evaluate the environmental impact of genotoxins in aquatic environments. It …
The comet assay in animal models: From bugs to whales–(Part 1 Invertebrates)
The comet assay, also called single cell gel electrophoresis, is a sensitive, rapid and low-
cost technique for quantifying and analysing DNA damage and repair at the level of …
cost technique for quantifying and analysing DNA damage and repair at the level of …
Genotoxicity biomarkers in aquatic bioindicators
C Bolognesi, S Cirillo - Current Zoology, 2014 - academic.oup.com
Pollution of the aquatic environment is an ever-growing problem, as waters are the ultimate
sink for the large number of xenobiotics from multiple sources. DNA damaging agents have …
sink for the large number of xenobiotics from multiple sources. DNA damaging agents have …
The use of freshwater planarians in environmental toxicology studies: advantages and potential
JP Wu, MH Li - Ecotoxicology and environmental safety, 2018 - Elsevier
Regarding the humane use of animals in scientific research, invertebrates are often
recommended in toxicological studies.“Freshwater planarians” refers to numerous free-living …
recommended in toxicological studies.“Freshwater planarians” refers to numerous free-living …
Relationships between seminal plasma metals/metalloids and semen quality, sperm apoptosis and DNA integrity
YX Wang, P Wang, W Feng, C Liu, P Yang… - Environmental …, 2017 - Elsevier
This study aimed to investigate the relationships between environmental exposure to
metals/metalloids and semen quality, sperm apoptosis and DNA integrity using the …
metals/metalloids and semen quality, sperm apoptosis and DNA integrity using the …
Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model
Copper (Cu) is a micronutrient essential for the biochemical functioning of numerous
processes in vertebrates but is also often present in the aquatic environment at …
processes in vertebrates but is also often present in the aquatic environment at …
Evaluation of in vivo genotoxicity of cypermethrin in Drosophila melanogaster using the alkaline Comet assay
I Mukhopadhyay, DK Chowdhuri, M Bajpayee… - …, 2004 - academic.oup.com
The single cell gel electrophoresis (SCGE) assay, also known as the Comet assay, is one of
the most promising genotoxicity tests developed in recent years to measure and analyse …
the most promising genotoxicity tests developed in recent years to measure and analyse …
Application of the micronucleus and comet assays to mussel Dreissena polymorpha haemocytes for genotoxicity monitoring of freshwater environments
Assessment of DNA damage is of primary concern when determining the pollution-related
stress in living organisms. To monitor genotoxicity of the freshwater environments we used …
stress in living organisms. To monitor genotoxicity of the freshwater environments we used …