Skin wound healing process and new emerging technologies for skin wound care and regeneration

EM Tottoli, R Dorati, I Genta, E Chiesa, S Pisani… - Pharmaceutics, 2020 - mdpi.com
Skin wound healing shows an extraordinary cellular function mechanism, unique in nature
and involving the interaction of several cells, growth factors and cytokines. Physiological …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Mesenchymal stem cells and immunomodulation: current status and future prospects

F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …

Mesenchymal stromal/stem cells in regenerative medicine and tissue engineering

REB Fitzsimmons, MS Mazurek, A Soos… - Stem cells …, 2018 - Wiley Online Library
As a result of over five decades of investigation, mesenchymal stromal/stem cells (MSCs)
have emerged as a versatile and frequently utilized cell source in the fields of regenerative …

Tissue-engineered bone immobilized with human adipose stem cells-derived exosomes promotes bone regeneration

W Li, Y Liu, P Zhang, Y Tang, M Zhou… - … applied materials & …, 2018 - ACS Publications
Exosomes, nanoscale extracellular vesicles functioning as cell-to-cell communicators, are
an emerging promising therapeutic in the field of bone tissue engineering. Here, we report …

Applications of mesenchymal stem cells in skin regeneration and rejuvenation

H Jo, S Brito, BM Kwak, S Park, MG Lee… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from adult stem cells.
Primary MSCs can be obtained from diverse sources, including bone marrow, adipose …

[HTML][HTML] Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells repair critical-sized bone defects through enhanced …

X Qi, J Zhang, H Yuan, Z Xu, Q Li, X Niu… - … journal of biological …, 2016 - ncbi.nlm.nih.gov
Bone defects caused by trauma, severe infection, tumor resection and skeletal abnormalities
are common osteoporotic conditions and major challenges in orthopedic surgery, and there …

Exosomes/tricalcium phosphate combination scaffolds can enhance bone regeneration by activating the PI3K/Akt signaling pathway

J Zhang, X Liu, H Li, C Chen, B Hu, X Niu, Q Li… - Stem cell research & …, 2016 - Springer
Background Recently, accumulating evidence has shown that exosomes, the naturally
secreted nanocarriers of cells, can exert therapeutic effects in various disease models in the …

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

J Zhang, J Guan, X Niu, G Hu, S Guo, Q Li, Z **e… - Journal of translational …, 2015 - Springer
Background Human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-
MSCs) have emerged as a promising alternative for stem cell transplantation therapy …

Concise review: the evolution of human pluripotent stem cell culture: from feeder cells to synthetic coatings

LG Villa-Diaz, AM Ross, J Lahann, PH Krebsbach - Stem cells, 2013 - academic.oup.com
Current practices to maintain human pluripotent stem cells (hPSCs), which include induced
pluripotent stem cells and embryonic stem cells, in an undifferentiated state typically depend …