Anti-tuberculosis treatment strategies and drug development: challenges and priorities
VA Dartois, EJ Rubin - Nature Reviews Microbiology, 2022 - nature.com
Despite two decades of intensified research to understand and cure tuberculosis disease,
biological uncertainties remain and hamper progress. However, owing to collaborative …
biological uncertainties remain and hamper progress. However, owing to collaborative …
The use and misuse of mathematical modeling for infectious disease policymaking: lessons for the COVID-19 pandemic
LP James, JA Salomon, CO Buckee… - Medical Decision …, 2021 - journals.sagepub.com
Mathematical modeling has played a prominent and necessary role in the current
coronavirus disease 2019 (COVID-19) pandemic, with an increasing number of models …
coronavirus disease 2019 (COVID-19) pandemic, with an increasing number of models …
Urogenital tuberculosis—epidemiology, pathogenesis and clinical features
A Muneer, B Macrae, S Krishnamoorthy… - Nature Reviews …, 2019 - nature.com
Tuberculosis (TB) is the most common cause of death from infectious disease worldwide. A
substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG …
substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG …
Quantifying progression and regression across the spectrum of pulmonary tuberculosis: a data synthesis study
Background Prevalence surveys show a substantial burden of subclinical (asymptomatic but
infectious) tuberculosis, from which individuals can progress, regress, or even persist in a …
infectious) tuberculosis, from which individuals can progress, regress, or even persist in a …
Self-clearance of Mycobacterium tuberculosis infection: implications for lifetime risk and population at-risk of tuberculosis disease
JC Emery, AS Richards, KD Dale… - … of the Royal …, 2021 - royalsocietypublishing.org
Background: it is widely assumed that individuals with Mycobacterium tuberculosis (Mtb)
infection remain at lifelong risk of tuberculosis (TB) disease. However, there is substantial …
infection remain at lifelong risk of tuberculosis (TB) disease. However, there is substantial …
Global, regional, and national burden of HIV-negative tuberculosis, 1990–2021: findings from the Global Burden of Disease Study 2021
SX Zhang, FY Miao, J Yang, WT Zhou, S Lv… - Infectious Diseases of …, 2024 - Springer
Background Tuberculosis (TB) is a major infectious disease with significant public health
implications. Its widespread transmission, prolonged treatment duration, notable side effects …
implications. Its widespread transmission, prolonged treatment duration, notable side effects …
Quantifying the rates of late reactivation tuberculosis: a systematic review
The risk of tuberculosis is greatest soon after infection, but Mycobacterium tuberculosis can
remain in the body latently, and individuals can develop disease in the future, sometimes …
remain in the body latently, and individuals can develop disease in the future, sometimes …
Potential impact of tuberculosis vaccines in China, South Africa, and India
More effective tuberculosis vaccines are needed to help reach World Health Organization
tuberculosis elimination goals. Insufficient evidence exists on the potential impact of future …
tuberculosis elimination goals. Insufficient evidence exists on the potential impact of future …
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
The knowns and unknowns of latent Mycobacterium tuberculosis infection
WH Boom, UE Schaible… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Humans have been infected with Mycobacterium tuberculosis (Mtb) for thousands of years.
While tuberculosis (TB), one of the deadliest infectious diseases, is caused by uncontrolled …
While tuberculosis (TB), one of the deadliest infectious diseases, is caused by uncontrolled …