Simple Summary Phenotypic diversity in tumors makes treatment difficult and leads to poor
prognosis. A better understanding of what causes intratumoral heterogeneity and …

Described herein is a protocol for producing a synthetic extracellular matrix that can be
modified in situ during three-dimensional cell culture. The hydrogel platform is established …

Toward the goal of establishing an engineered model of the vocal fold lamina propria (LP),
mesenchymal stem cells (MSCs) are encapsulated in hyaluronic acid (HA)‐based hydrogels …

The advent of the click chemistry paradigm has profoundly transformed the design of
functional polymeric materials. Among the various reactions in the click chemistry toolkit, the …

Hyaluronic acid (HA) is a natural, non‐sulfated glycosaminoglycan (GAG) present in ECM. It
is involved in different biological functions with appealing properties in cosmetics and …

Surface modification of materials with proteins has various biological applications, and
hence the methodology for surface modification needs to accommodate a wide range of …

Background: Despite significant advances in three-dimensional (3D) cell culture
technologies, creating accurate in vitro models that faithfully recapitulate complex in vivo …

Here we describe a cost-effective and simplified cell sorting method using tetrazine
bioorthogonal chemistry. We successfully isolated SKOV3 cells from complex mixtures …

To recapitulate prostate cancer metastasis, DU145 cells were cultured in a hyaluronic acid-
based, bioorthogonally constructed, protease-degradable hydrogel. In the presence of …

The extracellular matrix (ECM) is an important determinant of tissue specificity. The ECM
provides cell instructive signals to induce phenotypic changes and promote cell growth …