Myostatin (GDF-8) was discovered 25 years ago as a new transforming growth factor-β
family member that acts as a master regulator of skeletal muscle mass. Myostatin is made by …

Domestic animals are invaluable resources for study of the molecular architecture of
complex traits. Although the map** of quantitative trait loci (QTL) responsible for …

The genomic changes underlying both early and late stages of horse domestication remain
largely unknown. We examined the genomes of 14 early domestic horses from the Bronze …

Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …

An equine SNP genoty** array was developed and evaluated on a panel of samples
representing 14 domestic horse breeds and 18 evolutionarily related species. More than …

The molecular analysis of genes influencing human height has been notoriously difficult.
Genome-wide association studies (GWAS) for height in humans based on tens of thousands …

Background To date, genome-scale analyses in the domestic horse have been limited by
suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of …

The horse was domesticated only 5.5 KYA, thousands of years after dogs, cattle, pigs,
sheep, and goats. The horse nonetheless represents the domestic animal that most …

The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Body size is an important characteristic for horses of various breeds and essential for the
classification of ponies concerning the limit value of 148 cm (58.27 inches) height at the …