Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of cardiometabolic
syndrome, which often also includes obesity, diabetes, and dyslipidemia. It is rapidly …

The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Obesity has been described as a global epidemic and is a low-grade chronic inflammatory
disease that arises as a consequence of energy imbalance. Obesity increases the risk of …

Inflammation and hepatocyte injury and death are the hallmarks of nonalcoholic
steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease (NAFLD) …

Obesity-related hypogonadotropic hypogonadism is a well-characterized condition in men
(termed male obesity-related secondary hypogonadism; MOSH); however, an equivalent …

The finding of islet inflammation in type 2 diabetes (T2D) and its involvement in β cell
dysfunction has further highlighted the significance of inflammation in metabolic diseases …

Components of the immune system are altered in obesity and type 2 diabetes (T2D), with the
most apparent changes occurring in adipose tissue, the liver, pancreatic islets, the …

Depression and type 2 diabetes (T2D) are highly comorbid disorders that carry a large
public health burden. However, there is a clear lack of knowledge of the neural pathological …

Obesity is associated with metabolic alterations related to glucose homeostasis and
cardiovascular risk factors. These metabolic alterations are associated with low-grade …

Human gut microbiota has been increasingly recognized as a pivotal determinant of non-
alcoholic fatty liver disease (NAFLD). Apart from the changes in the composition of gut …