Frontotemporal lobar degeneration (FTLD) has been associated with toxic intracellular
aggregates of hyperphosphorylated tau (FTLD‐tau). Moreover, genetic studies identified …

An update on pathogenesis of Alzheimer's disease, the present document describes the
crosstalk between autophagy and inflammation in Alzheimer's disease progression by …

Abstract MECP2 duplication syndrome (MDS), a rare X‐linked genomic disorder affecting
predominantly males, is caused by duplication of the chromosomal region containing the …

Convolvulus pluricaulis (Shankhapushpi) has long been used as traditional herbal medicine
in India as nerve tonic. We studied the neuroprotective effects of C. pluricaulis extract …

Tauopathies, such as Alzheimer's disease (AD), are a group of disorders characterized
neuropathologically by intracellular toxic accumulations of abnormal protein aggregates …

Glia is pivotal in regulating neuronal stem cell proliferation, functioning, and nervous system
homeostasis, significantly influencing neuronal health and disorders. Dysfunction in glial …

Human life expectancy increases, but the disease-free part of lifespan (healthspan) and the
quality of life in old people may not show the same development. The situation poses …

Neurodegenerative disorders, including Alzheimer's (AD) and Parkinson's diseases (PD),
are characterised by the formation of aberrant assemblies of misfolded proteins. The …

Alzheimer's disease (AD) is the most abundant tauopathy and is characterized by Aβ-
derived plaques and tau-derived tangles, resulting from the unfolding of the corresponding …

Expression of MeCP2 must be carefully regulated as a reduction or increase results in
serious neurological disorders. We are studying transgenic mice in which the MeCP2 gene …