Conspectus Catalytic intermolecular hydroamination of alkenes is an atom-and step-
economical method for the synthesis of amines, which have important applications as …

Conspectus Alkenes are versatile compounds that are readily available on a large scale
from industry or through organic synthesis. The widespread occurrence of alkenes provides …

Chiral amines are commonly used in the pharmaceutical and agrochemical industries. The
strong demand for unnatural chiral amines has driven the development of catalytic …

Ketones are crucial intermediates in synthesis and frequent moieties in many products. The
direct regioselective synthesis of ketones from internal alkenes could simplify synthetic …

To increase the reliability and success rate of drug discovery, efforts have been made to
increase the C (sp 3) fraction and avoid flat molecules. sp 3-Rich enantiopure amines are …

An efficient and general radical hydroamination of alkenes using Co (salen) as catalyst, N‐
fluorobenzenesulfonimide (NFSI) and its analogues as both nitrogen source and oxidant …

We report a light-driven method for the intermolecular anti-Markovnikov hydroamination of
alkenes with primary heteroaryl amines. In this protocol, electron transfer between an amine …

Catalytic asymmetric hydroamination of alkenes with Lewis basic amines is of great interest
but remains a challenge in synthetic chemistry. Here, we developed a Co‐catalyzed …

Chirality conferral is fundamental for understanding the origin of life, and it is of direct
importance for synthesizing new pharmaceuticals in the face of growing antibiotic …

Chiral α-tertiary amines and related azacycles are sought-after compounds for drug
development. Despite progress in the catalytic asymmetric construction of aza-quaternary …