Targeting non-coding RNAs to overcome cancer therapy resistance
BQ Chen, MP Dragomir, C Yang, Q Li, D Horst… - Signal transduction and …, 2022 - nature.com
It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …
Tumor immune microenvironment lncRNAs
EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …
immune responses. The nature of their cell type-specific gene expression and other …
Long non-coding RNAs in the doxorubicin resistance of cancer cells
S Ashrafizaveh, M Ashrafizadeh, A Zarrabi… - Cancer Letters, 2021 - Elsevier
Chemotherapy is the main treatment used for cancer patients failing surgery. Doxorubicin
(DOX) is a well-known chemotherapeutic agent capable of suppressing proliferation in …
(DOX) is a well-known chemotherapeutic agent capable of suppressing proliferation in …
Long non-coding RNA mediated drug resistance in breast cancer
Breast cancer is one of the most prevalent cancers in women and a leading cause of
mortality. As per the GLOBCAN report of 2021, breast cancer has surpassed lung cancer …
mortality. As per the GLOBCAN report of 2021, breast cancer has surpassed lung cancer …
[HTML][HTML] Long non-coding RNA and RNA-binding protein interactions in cancer: experimental and machine learning approaches
Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …
comprise the bulk of the genome, is important for understanding virtually every hallmark of …
[HTML][HTML] LncRNA H19: A novel oncogene in multiple cancers
J Yang, M Qi, X Fei, X Wang, K Wang - International journal of …, 2021 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are a series of non-coding RNAs that lack open reading
frameworks. Accumulating evidence suggests important roles for lncRNAs in various …
frameworks. Accumulating evidence suggests important roles for lncRNAs in various …
CRISPR/Cas9 gene editing: a new approach for overcoming drug resistance in cancer
M Vaghari-Tabari, P Hassanpour… - Cellular & Molecular …, 2022 - Springer
The CRISPR/Cas9 system is an RNA-based adaptive immune system in bacteria and
archaea. Various studies have shown that it is possible to target a wide range of human …
archaea. Various studies have shown that it is possible to target a wide range of human …
Molecular mechanisms, biomarkers and emerging therapies for chemotherapy resistant TNBC
Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …
CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope
V Karn, S Sandhya, W Hsu, D Parashar… - Cancer Cell …, 2022 - Springer
Cancer is one of the major causes of mortality worldwide, therefore it is considered a major
health concern. Breast cancer is the most frequent type of cancer which affects women on a …
health concern. Breast cancer is the most frequent type of cancer which affects women on a …
Self‐stabilized supramolecular assemblies constructed from PEGylated dendritic peptide conjugate for augmenting tumor retention and therapy
X Zheng, D Pan, X Chen, L Wu, M Chen… - Advanced …, 2021 - Wiley Online Library
Supramolecular self‐assemblies of dendritic peptides with well‐organized nanostructures
have great potential as multifunctional biomaterials, yet the complex self‐assembly …
have great potential as multifunctional biomaterials, yet the complex self‐assembly …