The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …

Nonsteroidal anti-inflammatory drugs (NSAIDs) regulate inflammation, which is associated
with their role in preventing neurodegenerative diseases in epidemiological studies. It has …

Neurodegenerative disorders have a pathophysiology that heavily involves
neuroinflammation. In this study, we used lipopolysaccharide (LPS) to create a model of …

Aims Long-term neuroinflammation and brain dysfunction have frequently been reported in
sepsis survivors. In this study, the protective effect of memantine (an NMDA receptor …

Aim Sepsis-associated encephalopathy is a frequently observed consequence of sepsis,
often resulting in chronic brain inflammation and injury, ultimately leading to a range of …

Age-related cognitive decline, a common component of the brain aging process, is
associated with significant impairment in daily functioning and quality of life among geriatric …

Fibrosis is a pathological process in diabetic nephropathy that causes renal failure and
dysfunction. Given the known anti-diabetic effects of trans-Anethole (TA), we aimed to …

In recent years much focus has been on neuroimmune mechanisms of depression. As a
consequence, many preclinical and clinical trials have been performed examining potential …

Sepsis is associated with brain injury and acute brain inflammation, which can potentially
transition into chronic inflammation, triggering a cascade of inflammatory responses that …

Cognitive impairment has been known as a common consequence of brain inflammation.
Long‐term potentiation (LTP), the generally accepted cellular mechanism for memory …