Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson's disease
TA Alarcón, SM Presti-Silva, APT Simões… - Neural Regeneration …, 2023 - journals.lww.com
Parkinson's disease is the most common movement disorder, affecting about 1% of the
population over the age of 60 years. Parkinson's disease is characterized clinically by …
population over the age of 60 years. Parkinson's disease is characterized clinically by …
The neuroprotective effects of experience on cognitive functions: evidence from animal studies on the neurobiological bases of brain reserve
F Gelfo, L Mandolesi, L Serra, G Sorrentino… - Neuroscience, 2018 - Elsevier
Brain plasticity is the ability of the nervous system to change structurally and functionally in
response to experience. By sha** brain structure and function, experience leads to the …
response to experience. By sha** brain structure and function, experience leads to the …
Neuroprotective effect of crocin on substantia nigra in MPTP-induced Parkinson's disease model of mice
P Haeri, A Mohammadipour, Z Heidari… - Anatomical science …, 2019 - Springer
Parkinson's disease is caused by damage to substantia nigra dopaminergic neurons.
Factors such as oxidative stress, inflammatory factors, and acetylcholinesterase activity may …
Factors such as oxidative stress, inflammatory factors, and acetylcholinesterase activity may …
Poly (I: C)-induced maternal immune activation modifies ventral hippocampal regulation of stress reactivity: prevention by environmental enrichment
Environmental enrichment (EE) has been successfully implemented in human rehabilitation
settings. However, the mechanisms underlying its success are not understood. Incorporating …
settings. However, the mechanisms underlying its success are not understood. Incorporating …
Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients
Lepidium meyenii (Maca), originated from Peru, has been cultivated widely in China as a
popular health care food. However, the chemical and effective studies of Maca were less in …
popular health care food. However, the chemical and effective studies of Maca were less in …
Environmental enrichment cognitive neuroprotection in an experimental model of cerebral ischemia: biochemical and molecular aspects
LV Goncalves, AL Herlinger, TAA Ferreira… - Behavioural Brain …, 2018 - Elsevier
Stroke is considered a major cause of global morbidity. Currently, there are no effective
treatments for post-stroke cognitive impairment. Enriched environment (EE) has been …
treatments for post-stroke cognitive impairment. Enriched environment (EE) has been …
Diosgenin attenuates lipopolysaccharide-induced Parkinson's disease by inhibiting the TLR/NF-κB pathway
B Li, P Xu, S Wu, Z Jiang, Z Huang… - Journal of Alzheimer's …, 2018 - content.iospress.com
Background: Parkinson's disease (PD) is a neurodegenerative disease characterized by
loss of dopaminergic neurons in the substantia nigra. Diosgenin is a natural steroid saponin …
loss of dopaminergic neurons in the substantia nigra. Diosgenin is a natural steroid saponin …
Neurobehavioral changes arising from early life dopamine signaling perturbations
Dopamine (DA) signaling is critical to the modulation of multiple brain functions including
locomotion, reinforcement, attention and cognition. The literature provides strong evidence …
locomotion, reinforcement, attention and cognition. The literature provides strong evidence …
Enriched physical environment attenuates spatial and social memory impairments of aged socially isolated mice
L Wang, M Cao, T Pu, H Huang… - International Journal …, 2018 - academic.oup.com
Background Social isolation in the elderly is one of the principal health risks in an aging
society. Physical environmental enrichment is shown to improve sensory, cognitive, and …
society. Physical environmental enrichment is shown to improve sensory, cognitive, and …
Biochemical and behavioral effects of rosmarinic acid treatment in an animal model of Parkinson's disease induced by MPTP
SM Presti-Silva, AL Herlinger, C Martins-Silva… - Behavioural Brain …, 2023 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. The main therapeutic approach available nowadays relieves motor symptoms …
worldwide. The main therapeutic approach available nowadays relieves motor symptoms …