Ecology and evolution of Mycobacterium tuberculosis
S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …
The causative agents of TB are a group of closely related bacteria known as the …
Evolution and emergence of Mycobacterium tuberculosis
M Orgeur, C Sous, J Madacki… - FEMS microbiology …, 2024 - academic.oup.com
Tuberculosis (TB) remains one of the deadliest infectious diseases in human history,
prevailing even in the 21st century. The causative agents of TB are represented by a group …
prevailing even in the 21st century. The causative agents of TB are represented by a group …
Cutaneous mycobacterial infections
C Franco-Paredes, LA Marcos… - Clinical microbiology …, 2018 - journals.asm.org
Humans encounter mycobacterial species due to their ubiquity in different environmental
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …
A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
JCS Ngabonziza, C Loiseau, M Marceau… - Nature …, 2020 - nature.com
The human-and animal-adapted lineages of the Mycobacterium tuberculosis complex
(MTBC) are thought to have expanded from a common progenitor in Africa. However, the …
(MTBC) are thought to have expanded from a common progenitor in Africa. However, the …
Host evasion and exploitation schemes of Mycobacterium tuberculosis
Tuberculosis, an ancient disease of mankind, remains one of the major infectious causes of
human death. We examine newly discovered facets of tuberculosis pathogenesis and …
human death. We examine newly discovered facets of tuberculosis pathogenesis and …
Towards a new combination therapy for tuberculosis with next generation benzothiazinones
V Makarov, B Lechartier, M Zhang, J Neres… - EMBO molecular …, 2014 - embopress.org
The benzothiazinone lead compound, BTZ 043, kills Mycobacterium tuberculosis by
inhibiting the essential flavo‐enzyme DprE1, decaprenylphosphoryl‐beta‐D‐ribose 2 …
inhibiting the essential flavo‐enzyme DprE1, decaprenylphosphoryl‐beta‐D‐ribose 2 …
[PDF][PDF] Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs
Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …
disease models, due to ease of use and the presence of an innate immune system …
The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes
In this paper, we present the MycoBrowser portal (http://mycobrowser. epfl. ch/), a resource
that provides both in silico generated and manually reviewed information within databases …
that provides both in silico generated and manually reviewed information within databases …
Mechanisms of bacterial tolerance and persistence in the gastrointestinal and respiratory environments
R Trastoy, T Manso, L Fernández-García… - Clinical microbiology …, 2018 - journals.asm.org
Pathogens that infect the gastrointestinal and respiratory tracts are subjected to intense
pressure due to the environmental conditions of the surroundings. This pressure has led to …
pressure due to the environmental conditions of the surroundings. This pressure has led to …
Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution
HR Ramage, LE Connolly, JS Cox - PLoS genetics, 2009 - journals.plos.org
Toxin-antitoxin (TA) systems, stress-responsive genetic elements ubiquitous in microbial
genomes, are unusually abundant in the major human pathogen Mycobacterium …
genomes, are unusually abundant in the major human pathogen Mycobacterium …