• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Bicuspid aortic stenosis is a common pathology, typically seen in patients a decade younger
than those with tricuspid valves. Surgical aortic valve replacement has been the mainstay …

Direct oral anticoagulants (DOACs) have transformed the landscape of antithrombotic
therapy in the past two decades. However, there is uncertainty about when they should or …

Abstract Background and Aims Marfan syndrome (MFS) is a hereditary disorder primarily
caused by mutations in the FBN1 gene. Its critical cardiovascular manifestation is thoracic …

Abstract Background and Aims Lower extremity peripheral arterial disease (PAD) presents a
substantial disease burden, yet lifetime estimates remain scant. This nationwide study …

OBJECTIVES Mesenteric malperfusion in acute aortic dissection remains a life-threatening
complication with no standardized treatment strategy. This study aimed to describe and …

There is clear scientific evidence that regular physical activity improves cardiovascular
prognosis. 1 Therefore, exercise training is highly recommended in clinical guidelines …

Background: The relationship between alcohol consumption and vascular structure and
arterial stiffness is not clear, especially in people diagnosed with persistent COVID. The aim …

A new insight into oxidative stress is based on oxidative deoxyribonucleic acid (DNA)
damage. DNA is the pivotal biopolymer for life and health. Arterial hypertension (HT) is a …

Aims To assess the presence and the extent of an “aortic remodeling” in elite athletes.
Methods A systematic review and meta-analysis of literature were conducted for studies …