Mechanics, mechanobiology, and modeling of human abdominal aorta and aneurysms

JD Humphrey, GA Holzapfel - Journal of biomechanics, 2012 - Elsevier
Biomechanical factors play fundamental roles in the natural history of abdominal aortic
aneurysms (AAAs) and their responses to treatment. Advances during the past two decades …

Biochemomechanics of intraluminal thrombus in abdominal aortic aneurysms

JS Wilson, L Virag, P Di Achille… - Journal of …, 2013 - asmedigitalcollection.asme.org
Most computational models of abdominal aortic aneurysms address either the
hemodynamics within the lesion or the mechanics of the wall. More recently, however, some …

A machine learning approach to investigate the relationship between shape features and numerically predicted risk of ascending aortic aneurysm

L Liang, M Liu, C Martin, JA Elefteriades… - … and modeling in …, 2017 - Springer
Geometric features of the aorta are linked to patient risk of rupture in the clinical decision to
electively repair an ascending aortic aneurysm (AsAA). Previous approaches have focused …

Spatial orientation of collagen fibers in the abdominal aortic aneurysm's wall and its relation to wall mechanics

TC Gasser, S Gallinetti, X **ng, C Forsell… - Acta biomaterialia, 2012 - Elsevier
Collagen is the most abundant protein in mammals and provides the abdominal aortic
aneurysm (AAA) wall with mechanical strength, stiffness and toughness. Specifically, the …

[HTML][HTML] A novel strategy to translate the biomechanical rupture risk of abdominal aortic aneurysms to their equivalent diameter risk: method and retrospective …

TC Gasser, A Nchimi, J Swedenborg, J Roy… - European Journal of …, 2014 - Elsevier
Objective To translate the individual abdominal aortic aneurysm (AAA) patient's
biomechanical rupture risk profile to risk-equivalent diameters, and to retrospectively test …

Measuring and modeling patient-specific distributions of material properties in abdominal aortic aneurysm wall

C Reeps, A Maier, J Pelisek, F Härtl… - … and modeling in …, 2013 - Springer
Both the clinically established diameter criterion and novel approaches of computational
finite element (FE) analyses for rupture risk stratification of abdominal aortic aneurysms …

A longitudinal comparison of hemodynamics and intraluminal thrombus deposition in abdominal aortic aneurysms

A Arzani, GY Suh, RL Dalman… - American Journal of …, 2014 - journals.physiology.org
Abdominal aortic aneurysm (AAA) is often accompanied by in traluminal thrombus (ILT),
which complicates AAA progression and risk of rupture. Patient-specific computational fluid …

Quantitative assessment of abdominal aortic aneurysm geometry

J Shum, G Martufi, E Di Martino, CB Washington… - Annals of biomedical …, 2011 - Springer
Recent studies have shown that the maximum transverse diameter of an abdominal aortic
aneurysm (AAA) and expansion rate are not entirely reliable indicators of rupture potential …

Towards efficient uncertainty quantification in complex and large-scale biomechanical problems based on a Bayesian multi-fidelity scheme

J Biehler, MW Gee, WA Wall - Biomechanics and modeling in …, 2015 - Springer
In simulation of cardiovascular processes and diseases patient-specific model parameters,
such as constitutive properties, are usually not easy to obtain. Instead of using population …

Geometric and biomechanical modeling aided by machine learning improves the prediction of growth and rupture of small abdominal aortic aneurysms

M Lindquist Liljeqvist, M Bogdanovic, A Siika… - Scientific reports, 2021 - nature.com
It remains difficult to predict when which patients with abdominal aortic aneurysm (AAA) will
require surgery. The aim was to study the accuracy of geometric and biomechanical analysis …