Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all
multicellular organisms to control cell proliferation and maintain tissue homeostasis as well …

Anti‐tumour therapies based on the use pro‐apoptotic receptor agonists, including TNF‐
related apoptosis‐inducing ligand (TRAIL) or monoclonal antibodies targeting TRAIL‐R1 or …

Probiotic microorganisms such as lactic acid bacteria (LAB) exert a number of strain-specific
health-promoting activities attributed to their immunomodulatory, anti-inflammatory and anti …

Dysregulated cellular apoptosis and resistance to cell death are hallmarks of neoplastic
initiation and disease progression. Therefore, the development of agents that overcome …

Evasion from apoptosis is an important hallmark of cancer cells. Alterations of apoptosis
pathways are especially critical as they confer resistance to conventional anti-cancer …

Cellular FLICE (FADD-like IL-1beta-converting enzyme)-inhibitory protein (c-FLIP) is a major
resistance factor and critical anti-apoptotic regulator that inhibits tumor necrosis factor-alpha …

Cellular-FLICE inhibitory protein (c-FLIP) is a key anti-apoptotic regulator that inhibits cell
death mediated by the death receptors Fas, DR4, DR5, and TNF-R1. Three splice variants of …

Probiotic bacteria are receiving growing interest, particularly for the preparation of functional
foods. In the present study, eight Lactobacillus strains, newly isolated from infant feces, were …

Cellular FLICE-like inhibitory protein (c-FLIP) has been identified as a protease-dead,
procaspase-8-like regulator of death ligand-induced apoptosis, based on observations that c …

Resistance to chemotherapy limits the effectiveness of current cancer therapies, including
those used to treat colorectal cancer, which is the second most common cause of cancer …