Retinal neurodegeneration as an early manifestation of diabetic eye disease and potential neuroprotective therapies
Abstract Purpose of Review Diabetic retinopathy (DR) is a major cause of visual impairment
and blindness throughout the world. Microvascular changes have long been regarded …
and blindness throughout the world. Microvascular changes have long been regarded …
Neuroprotection as a therapeutic target for diabetic retinopathy
C Hernández, M Dal Monte, R Simó… - Journal of diabetes …, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is a multifactorial progressive disease of the retina and a leading
cause of vision loss. DR has long been regarded as a vascular disorder, although neuronal …
cause of vision loss. DR has long been regarded as a vascular disorder, although neuronal …
Multidimensional functional and structural evaluation reveals neuroretinal impairment in early diabetic retinopathy
KA Joltikov, VM de Castro, JR Davila… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: To test whether quantitative functional tests and optical coherence tomography
(OCT)-defined structure can serve as effective tools to diagnose and monitor early diabetic …
(OCT)-defined structure can serve as effective tools to diagnose and monitor early diabetic …
Neuroinflammation and oxidative stress act in concert to promote neurodegeneration in the diabetic retina and optic nerve: galectin-3 participation
HR Mendonça, R Carpi-Santos… - Neural regeneration …, 2020 - journals.lww.com
Diabetes is a lifelong disease characterized by glucose metabolic imbalance, in which low
insulin levels or impaired insulin signaling lead to hyperglycemic state. Within 20 years of …
insulin levels or impaired insulin signaling lead to hyperglycemic state. Within 20 years of …
Diabetic retinopathy: important biochemical alterations and the main treatment strategies
AS ValdezGuerrero, JC Quintana-Pérez… - Canadian Journal of …, 2021 - Elsevier
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by impaired glucose
homeostasis, insulin resistance and hyperglycemia. Among its serious multisystemic …
homeostasis, insulin resistance and hyperglycemia. Among its serious multisystemic …
A critical review: psychophysical assessments of diabetic retinopathy
XD Chen, TW Gardner - Survey of ophthalmology, 2021 - Elsevier
Diabetic retinal disease remains a leading cause of vision loss despite currently available
screening methods, ocular treatments, and efforts to control metabolic dysfunction. It is now …
screening methods, ocular treatments, and efforts to control metabolic dysfunction. It is now …
Prediabetes influences the structure of the macula: thinning of the macula in the Northern Finland Birth Cohort
JM Huru, I Leiviskä, V Saarela… - British Journal of …, 2021 - bjo.bmj.com
Background/Aim The aim of this study was to evaluate the effect of prediabetes and diabetes
on macular thickness and retinal vascular calibres in our population-based cohort (Northern …
on macular thickness and retinal vascular calibres in our population-based cohort (Northern …
Role of ω3 polyunsaturated fatty acids in diabetic retinopathy: a morphological and metabolically cross talk among blood retina barriers damage, autoimmunity and …
AR Eynard, G Repossi - Lipids in Health and Disease, 2019 - Springer
Vision disorders are one of the most serious complications of diabetes mellitus (DM)
affecting the quality of life of patients and eventually cause blindness. The ocular lesions in …
affecting the quality of life of patients and eventually cause blindness. The ocular lesions in …
Impairment of colour vision in diabetes with no retinopathy: Sankara Nethralaya diabetic retinopathy epidemiology and molecular genetics study (SNDREAMS-II …
Purpose To assess impairment of colour vision in type 2 diabetics with no diabetic
retinopathy and elucidate associated risk factors in a population-based cross-sectional …
retinopathy and elucidate associated risk factors in a population-based cross-sectional …
Functional outcome of macular edema in different retinal disorders
O Tomkins-Netzer, F Ismetova, A Bar… - Progress in retinal and …, 2015 - Elsevier
Macular edema accompanies many ocular pathologies, affecting visual function and is an
important factor in treatment decisions and disease outcome. Though visual acuity is …
important factor in treatment decisions and disease outcome. Though visual acuity is …