The identification of new bioactive compounds derived from medicinal plants with significant
therapeutic properties has attracted considerable interest in recent years. Such is the case of …

Abstract Signal Transducers and Activators of Transcription (STATs) comprise an important
class of transcription factors that have been implicated in a wide variety of essential cellular …

Despite the advancement in the well-equipped and sophisticated laboratories and facilities,
cancer remains to be a major cause of death worldwide. Consequently, further investigation …

Signaling via the phosphatidylinositol-3 kinase (PI3K)/Akt/mammalian target of rapamycin
(mTOR) is crucial for divergent physiological processes including transcription, translation …

Celastrol is a quinone methyl triterpenoid monomeric ingredient extracted from the root of
Tripterygium wilfordii. Celastrol shows potential pharmacological activities in various …

Bioactive compounds from medicinal plants with anticancer and anti-inflammatory effects
have become key resources in drug discovery fields for the treatment of various …

In the recent years, much attention has been focused on identifying bioactive compounds
from medicinal plants that could be employed in therapeutics, which is attributed to their …

The NF-kB pathway, which is ubiquitous in nature and evolutionarily conserved in most cell
types, 1 controls the expression of genes involved in multiple physiologic processes …

Invasion and metastasis are the main causes of treatment failure and death in breast cancer.
Thus, novel invasion-based therapies such as those involving natural agents are urgently …

Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …