Modulation of cardiac contractility by the phopholamban/SERCA2a regulatome
EG Kranias, RJ Hajjar - Circulation research, 2012 - Am Heart Assoc
Heart disease remains the leading cause of death and disability in the Western world.
Current therapies aim at treating the symptoms rather than the subcellular mechanisms …
Current therapies aim at treating the symptoms rather than the subcellular mechanisms …
Neuropathy-and myopathy-associated mutations in human small heat shock proteins: characteristics and evolutionary history of the mutation sites
Mutations in four of the ten human small heat shock proteins (sHSP) are associated with
various forms of motor neuropathies and myopathies. In HspB1, HspB3, and HspB8 all …
various forms of motor neuropathies and myopathies. In HspB1, HspB3, and HspB8 all …
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death
J Qian, X Ren, X Wang, P Zhang, WK Jones… - Circulation …, 2009 - Am Heart Assoc
Rationale: The levels of a small heat shock protein (Hsp) 20 and its phosphorylation are
increased on ischemic insults, and overexpression of Hsp20 protects the heart against …
increased on ischemic insults, and overexpression of Hsp20 protects the heart against …
Truncation attenuates molecular chaperoning and apoptosis inhibition by p26, a small heat shock protein from Artemia franciscana
Y Wu, TH MacRae - Biochemistry and Cell Biology, 2010 - cdnsciencepub.com
The small heat shock proteins (sHSPs), which prevent irreversible protein denaturation and
inhibit apoptosis, consist of an amino-terminus, the canonical α-crystallin domain, and a …
inhibit apoptosis, consist of an amino-terminus, the canonical α-crystallin domain, and a …
Étude de la structure et de la fonction de la petite protéine de choc thermique DmHsp27
MT Moutaoufik - 2017 - library-archives.canada.ca
Les petites protéines de choc thermique (sHsps: small heat shock proteins) sont présentes
en nombre variable dans tous les organismes. Le génome de Drosophila melanogaster …
en nombre variable dans tous les organismes. Le génome de Drosophila melanogaster …