Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Short chain fatty acids (SCFAs)-mediated gut epithelial and immune regulation and its relevance for inflammatory bowel diseases

D Parada Venegas, MK De la Fuente… - Frontiers in …, 2019 - frontiersin.org
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel
Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial …

[HTML][HTML] The role of short-chain fatty acids from gut microbiota in gut-brain communication

YP Silva, A Bernardi, RL Frozza - Frontiers in endocrinology, 2020 - frontiersin.org
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …

A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The health benefits of dietary fibre

TM Barber, S Kabisch, AFH Pfeiffer, MO Weickert - Nutrients, 2020 - mdpi.com
Background: Dietary fibre consists of non-digestible forms of carbohydrate, usually as
polysaccharides that originate from plant-based foods. Over recent decades, our diet within …

The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology

A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut
microbial alteration, also known as dysbiosis, is a condition associated not only with …

You are what you eat: diet, health and the gut microbiota

N Zmora, J Suez, E Elinav - Nature reviews Gastroenterology & …, 2019 - nature.com
Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces sha** the architecture and functionality of resident …

The impact of the gut microbiome on extra-intestinal autoimmune diseases

E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

Interactions between the microbiota, immune and nervous systems in health and disease

TC Fung, CA Olson, EY Hsiao - Nature neuroscience, 2017 - nature.com
The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively
called the gut microbiota, profoundly influences many aspects of host physiology, including …

Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

D Erny, N Dokalis, C Mezö, A Castoldi, O Mossad… - Cell Metabolism, 2021 - cell.com
As tissue macrophages of the central nervous system (CNS), microglia constitute the pivotal
immune cells of this organ. Microglial features are strongly dependent on environmental …