Sepsis is the life-threatening organ dysfunction caused by a dysregulated host response to
infection and is the leading cause of death in intensive care units. Cardiac dysfunction …

Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Remarkable progress has been made in the development of new therapies for cancer,
dramatically changing the landscape of treatment approaches for several malignancies and …

Abstract Purpose of Review To briefly review epidemiology and pathophysiology of SICM
and provide a more extensive review of the data on diagnostic and management strategies …

Sepsis, severe sepsis, and septic shock represent increasingly severe systemic
inflammatory responses to infection. Sepsis is common in the aging population, and it …

Importance Patients with septic shock undergo adrenergic stress, which affects cardiac,
immune, inflammatory, and metabolic pathways. β-Blockade may attenuate the adverse …

The term acute liver failure (ALF) is frequently applied as a generic expression to describe
patients presenting with or develo** an acute episode of liver dysfunction. In the context of …

Infections represent a common health problem in people of all ages. Usually, the response
given to them is appropriate and so little treatment is needed. Sometimes, however, the …

Objectives: To describe, with an emphasis on clinical applications, what is known about the
pathophysiology, management, and implications of septic cardiomyopathy in the adult ICU …

Septic cardiomyopathy is a key feature of sepsis-associated cardiovascular failure. Despite
the lack of consistent diagnostic criteria, patients typically exhibit ventricular dilatation …