Natural Killer (NK) cells and CD8+ cytotoxic T cells are two types of immune cells that can
kill target cells through similar cytotoxic mechanisms. With the remarkable success of …

Natural killer (NK) cells can swiftly kill multiple adjacent cells if these show surface markers
associated with oncogenic transformation. This property, which is unique among immune …

Natural killer (NK) cells belong to the innate immune system and contribute to protecting the
host through killing of infected, foreign, stressed or transformed cells. Additionally, via …

Natural killer (NK) cells are unique immune effectors able to kill cancer cells by direct
recognition of surface ligands, without prior sensitization. Allogeneic NK transfer is a highly …

Highlights•CAR T cells are associated with unique side-effects.•Cytokine release syndrome
(CRS), immune effector cell-associated neurotoxicity syndrome (ICANS) and cytopenias are …

Chimeric antigen receptor (CAR) T cells provide new therapeutic options for patients with
relapsed/refractory hematologic malignancies. However, neurotoxicity is a frequent, and …

Recent studies have demonstrated the potential of natural killer (NK) cells in immunotherapy
to treat multiple types of cancer. NK cells are innate lymphoid cells that play essential roles …

Allogeneic natural killer (NK) cell adoptive transfer has shown the potential to induce
remissions in relapsed or refractory leukemias and lymphomas, but strategies to enhance …

In vivo expansion of haploidentical natural killer (NK) cell infusions with interleukin-2 (IL-2)
can induce remission of refractory acute myeloid leukemia, but efficacy may be hampered by …

Natural killer (NK) cell-based immunotherapies are attracting increasing interest in the field
of cancer treatment. Early clinical trials have shown promising outcomes, alongside …