Emerging concepts in the science of vaccine adjuvants

B Pulendran, P S. Arunachalam… - Nature Reviews Drug …, 2021 - nature.com
Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Engineering robust Ag‐decorated polydopamine nano‐photothermal platforms to combat bacterial infection and prompt wound healing

X Qi, Y Huang, S You, Y **ang, E Cai, R Mao… - Advanced …, 2022 - Wiley Online Library
Polydopamine (PDA) nanoparticles have emerged as an attractive biomimetic photothermal
agent in photothermal antibacterial therapy due to their ease of synthesis, good …

Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Designing spatial and temporal control of vaccine responses

GA Roth, VCTM Picece, BS Ou, W Luo… - Nature Reviews …, 2022 - nature.com
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

All-in-one: Harnessing multifunctional injectable natural hydrogels for ordered therapy of bacteria-infected diabetic wounds

X Qi, Y **ang, E Cai, S You, T Gao, Y Lan… - Chemical Engineering …, 2022 - Elsevier
Current treatments for diabetic wounds remain unsatisfactory in clinical practice due to the
risk of bacterial infection, oxidative damage, and impaired angiogenesis during healing …

Sustainable cellulose and its derivatives for promising biomedical applications

W Cheng, Y Zhu, G Jiang, K Cao, S Zeng… - Progress in Materials …, 2023 - Elsevier
Novel biomedical materials provide a new horizon for the diagnosis/treatment of diseases
and tissue repair. Cellulose, mainly found in trees and other biomass, is one of the most …

[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors

AK Grosskopf, L Labanieh, DD Klysz, GA Roth, P Xu… - Science …, 2022 - science.org
Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but
traditional approaches to ACT are poorly effective in treating solid tumors observed …