The prevalence of alcohol use disorder (AUD) has been steadily increasing over the past
decade. In parallel, alcohol-associated liver disease (ALD) has been increasing at an …

The legitimacy of nonsubstance addictions has received increased attention from clinicians,
researchers and the general population as more and more individuals report symptoms …

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the
effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular …

Addictive disorders are partly heritable, chronic, relapsing conditions that account for a
tremendous disease burden. Currently available addiction pharmacotherapies are only …

The basic concepts underlying compulsive, impulsive and addictive behaviours overlap,
which may help explain why laymen use these expressions interchangeably. Although there …

Objective: Severe drinking can cause serious morbidity and death. Because the serotonin
transporter (5-HTT) is an important regulator of neuronal 5-HT function, allelic differences at …

Alcoholism remains a serious cause of morbidity and mortality despite progress through
neurobiological research in identifying new pharmacological strategies for its treatment …

Serotonin (5-HT) regulates important biological and psychological processes including
mood, and may be associated with the development of several psychiatric disorders. An …

Alcohol dependence represents a chronic and relapsing disease affecting nearly 10% of the
general population both in the USA and in Europe, with a widespread burden of morbidity …

Research on the concept of craving may lead to better understanding of the biobehavioural
circuitries that contribute to the complexity of alcohol use disorders (AUDs). The experiences …