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Skin microbiota–host interactions
The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi
and viruses. These microbes—collectively referred to as the skin microbiota—are …
and viruses. These microbes—collectively referred to as the skin microbiota—are …
Role of apoptosis in disease
Since the initial description of apoptosis, a number of different forms of cell death have been
described. In this review we will focus on classic caspase-dependent apoptosis and its …
described. In this review we will focus on classic caspase-dependent apoptosis and its …
Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …
Macrophages in tuberculosis: friend or foe
Tuberculosis (TB) remains one of the greatest threats to human health. The causative
bacterium, Mycobacterium tuberculosis (Mtb), is acquired by the respiratory route. It is …
bacterium, Mycobacterium tuberculosis (Mtb), is acquired by the respiratory route. It is …
Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors
Mycobacterium tuberculosis survives in antigen-presenting cells (APCs) such as
macrophages and dendritic cells. APCs present antigens in association with major …
macrophages and dendritic cells. APCs present antigens in association with major …
Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice
Bacteria naturally release membrane vesicles (MVs) under a variety of growth environments.
Their production is associated with virulence due to their capacity to concentrate toxins and …
Their production is associated with virulence due to their capacity to concentrate toxins and …
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response
The cell wall component lipoarabinomannan (ManLAM) from Mycobacterium tuberculosis is
involved in the inhibition of phagosome maturation, apoptosis and interferon (IFN)‐γ …
involved in the inhibition of phagosome maturation, apoptosis and interferon (IFN)‐γ …
Cells of the synovium in rheumatoid arthritis. Macrophages
RW Kinne, B Stuhlmüller, GR Burmester - Arthritis research & therapy, 2007 - Springer
The multitude and abundance of macrophage-derived mediators in rheumatoid arthritis and
their paracrine/autocrine effects identify macrophages as local and systemic amplifiers of …
their paracrine/autocrine effects identify macrophages as local and systemic amplifiers of …
Mycobacterium tuberculosis nuoG Is a Virulence Gene That Inhibits Apoptosis of Infected Host Cells
K Velmurugan, B Chen, JL Miller, S Azogue… - PLoS …, 2007 - journals.plos.org
The survival and persistence of Mycobacterium tuberculosis depends on its capacity to
manipulate multiple host defense pathways, including the ability to actively inhibit the death …
manipulate multiple host defense pathways, including the ability to actively inhibit the death …
[HTML][HTML] Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells
Mycobacterium tuberculosis promotes its replication by inhibiting the apoptosis of infected
macrophages. A proapoptotic M. tuberculosis mutant lacking nuoG, a subunit of the type I …
macrophages. A proapoptotic M. tuberculosis mutant lacking nuoG, a subunit of the type I …