Highlights•Complex substrates influence microbial ecology differently than simple
substrates.•Division of labor (DOL) in microbiomes can arise in polysaccharide …

Highlights•Xyloglucans comprise a family of ubiquitous, complex plant polysaccharides.•
Microbe and plants have evolved bespoke enzymes to address xyloglucan complexity.• …

Increased dietary fiber consumption has been shown to increase human gut microbial
diversity, but the mechanisms driving this effect remain unclear. One possible explanation is …

Anaerobic fungi found in the guts of large herbivores are prolific biomass degraders whose
genomes harbor a wealth of carbohydrate-active enzymes (CAZymes), of which only a …

Glycoside hydrolases (GHs) are known to depolymerize polysaccharides into oligo-/mono-
saccharides, they are extensively used as additives for both animals feed and our food. Here …

Genome sequencing has revealed substantial variation in the predicted abilities of
individual species within animal gut microbiota to metabolize the complex carbohydrates …

Mixed-linkage β (1, 3)/β (1, 4)-glucan (MLG) is abundant in the human diet through the
ingestion of cereal grains and is widely associated with healthful effects on metabolism and …

The recent classification of glycoside hydrolase family 5 (GH5) members into subfamilies
enhances the prediction of substrate specificity by phylogenetic analysis. However, the small …

Abstract Background Xyloglucan (XyG) is a ubiquitous and fundamental polysaccharide of
plant cell walls. Due to its structural complexity, XyG requires a combination of backbone …

Broad-specificity glycoside hydrolases (GHs) contribute to plant biomass hydrolysis by
degrading a diverse range of polysaccharides, making them useful catalysts for renewable …