Background Approximately 20% of all cancer patients will develop brain metastases in their
lifespan. The standard of care for patients with multiple brain metastases is whole-brain …

Early-life stress (ELS) may affect brain maturation and neuroimmune interactions and,
consequently, the inflammatory response to subsequent environmental factors later in life …

Psychostimulants alter cellular morphology and activate neuroimmune signaling in a
number of brain regions, yet few prior studies have investigated their persistence beyond …

A total of 1 in 20 infants born annually are exposed to alcohol prenatally, which disrupts
neurodevelopment and results in several disorders categorized under the umbrella term …

Pregnancy and motherhood can have long-term effects on cognition and brain aging in both
humans and rodents. Estrogens are related to cognitive function and neuroplasticity …

Disruption of circadian rhythms has detrimental host consequences. Indeed, both clinical
and foundational science demonstrate a clear relationship between disruption of circadian …

Birth is preceded by inflammation at the fetal/maternal interface. Additionally, the newborn
experiences stimuli that under any other circumstance could elicit an immune response. It is …

Background/Objective: The blood–brain barrier (BBB) is selectively permeable, but it also
poses significant challenges for treating CNS diseases. Low-intensity focused ultrasound …

Chemotherapy is more effective in the treatment of peripheral tumors than brain metastases,
likely reflecting the reduced ability of chemotherapy to cross the blood-brain barrier (BBB) …

Introduction Patients with Neurofibromatosis type 1 (NF1), the most common
neurocutaneous disorder, can develop several neurological manifestations that include …