Antigen processing and presentation are the cornerstones of adaptive immunity. B cells
cannot generate high-affinity antibodies without T cell help. CD4+ T cells, which provide …

Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …

Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged
receptors, a hallmark of adaptive lymphocytes. In some people infected with human …

The unconventional T cell compartment encompasses a variety of cell subsets that straddle
the line between innate and adaptive immunity, often reside at mucosal surfaces and can …

Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft
recipient and AIDS patients. More recently, it has been recognized as a pathogen for those …

Avoiding the immune rejection of transplanted T cells is central to the success of allogeneic
cancer immunotherapies. One solution to protecting T-cell grafts from immune rejection …

Natural killer (NK) cells are innate lymphocytes that are crucial for the control of infections
and malignancies. NK cells express a variety of inhibitory and activating receptors that …

A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host …

During human CMV infection, there is a preferential expansion of natural killer (NK) cells
expressing the activating CD94–NKG2C receptor complex, implicating this receptor in the …

Natural killer (NK) cells are lymphocytes that contribute to the early immune responses to
viruses. NK cells are innate immune cells that do not express rearranged antigen receptors …