Microglia are resident cells of the brain that regulate brain development, maintenance of
neuronal networks, and injury repair. Microglia serve as brain macrophages but are distinct …

Prion diseases are progressive, incurable and fatal neurodegenerative conditions. The term
'prion'was first nominated to express the revolutionary concept that a protein could be …

Oligodendrocyte-lineage cells, including NG2 glia, undergo prominent changes in various
neurodegenerative disorders. Here, we identify a neuroprotective role for NG2 glia against …

Abstract The Janus Kinase/Signal Transducers and Activators of Transcription (JAK/STAT)
signaling pathway is utilized by numerous cytokines and interferons, and is essential for the …

Macroautophagy/autophagy is a lysosome-dependent catabolic process for the turnover of
proteins and organelles in eukaryotes. Autophagy plays an important role in immunity and …

Aims Aircraft noise causes endothelial dysfunction, oxidative stress, and inflammation.
Transportation noise increases the incidence of coronary artery disease, hypertension, and …

Macrophages are specialized cells that control tissue homeostasis. They include non-
resident and tissue-resident macrophage populations which are characterized by the …

Recent findings have highlighted the role of microglia in orchestrating normal development
and refining neural network connectivity in the healthy CNS. Microglia are not only vital cells …

Prion diseases are rapidly progressive, incurable neurodegenerative disorders caused by
misfolded, aggregated proteins known as prions, which are uniquely infectious. Remarkably …

Drug addiction is a chronic and debilitating disease that is considered a global health
problem. Various cell types in the brain are involved in the progression of drug addiction …