A guide to the organ-on-a-chip
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …
[HTML][HTML] 3D cell culture systems: tumor application, advantages, and disadvantages
O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …
been used in cancer research. However, this system cannot be fully translated into clinical …
Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures
Three-dimensional hydrogel-based organ-like cultures can be applied to study
development, regeneration, and disease in vitro. However, the control of engineered …
development, regeneration, and disease in vitro. However, the control of engineered …
[HTML][HTML] Biomaterials to enhance stem cell transplantation
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …
medicine approaches and open promising avenues to repair, replace, and regenerate …
Organic Bioelectronics for In Vitro Systems
Bioelectronics have made strides in improving clinical diagnostics and precision medicine.
The potential of bioelectronics for bidirectional interfacing with biology through continuous …
The potential of bioelectronics for bidirectional interfacing with biology through continuous …
Use of Bombyx mori silk fibroin in tissue engineering: From cocoons to medical devices, challenges, and future perspectives
A Bucciarelli, A Motta - Biomaterials Advances, 2022 - Elsevier
Silk fibroin has become a prominent material in tissue engineering (TE) over the last 20
years with almost 10,000 published works spanning in all the TE applications, from skeleton …
years with almost 10,000 published works spanning in all the TE applications, from skeleton …
Ultrasound-assisted tissue engineering
Combining cells, biomaterials and bioactive factors with biophysical cues to engineer cell
and tissue constructs can address various applications, such as regenerative and …
and tissue constructs can address various applications, such as regenerative and …
Biomaterials to enhance adoptive cell therapy
N Eckman, A Nejatfard, R Cavet… - Nature Reviews …, 2024 - nature.com
Adoptive cell therapy (ACT) harnesses the capabilities of immune cells to fight complex
diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …
diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …
A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it
A Varone, JK Nguyen, L Leng, R Barrile, J Sliz… - Biomaterials, 2021 - Elsevier
Successful translation of in vivo experimental data to human patients is an unmet need and
a bottleneck in the development of effective therapeutics. Organ-on-Chip technology aims to …
a bottleneck in the development of effective therapeutics. Organ-on-Chip technology aims to …
[HTML][HTML] Bioprinting and differentiation of adipose-derived stromal cell spheroids for a 3D breast cancer-adipose tissue model
H Horder, M Guaza Lasheras, N Grummel… - Cells, 2021 - mdpi.com
Biofabrication, including printing technologies, has emerged as a powerful approach to the
design of disease models, such as in cancer research. In breast cancer, adipose tissue has …
design of disease models, such as in cancer research. In breast cancer, adipose tissue has …