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Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine
C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
Eosinophil–lymphocyte interactions in the tumor microenvironment and cancer immunotherapy
Eosinophils are important effector cells and therapeutic targets in allergic diseases.
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …
EAACI molecular allergology user's guide 2.0
S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19
Abstract Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …
Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion
Abstract Interleukin-33 (IL-33), an epithelial cell-derived cytokine that responds rapidly to
environmental insult, has a critical role in initiating airway inflammatory diseases. However …
environmental insult, has a critical role in initiating airway inflammatory diseases. However …
When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death
FJ Bock, JS Riley - Cell Death & Differentiation, 2023 - nature.com
Apoptosis is a regulated cellular pathway that ensures that a cell dies in a structured fashion
to prevent negative consequences for the tissue or the organism. Dysfunctional apoptosis is …
to prevent negative consequences for the tissue or the organism. Dysfunctional apoptosis is …
Protease allergens as initiators–regulators of allergic inflammation
Tremendous progress in the last few years has been made to explain how seemingly
harmless environmental proteins from different origins can induce potent Th2‐biased …
harmless environmental proteins from different origins can induce potent Th2‐biased …
[HTML][HTML] Mechanistic insights into eosinophilic esophagitis: therapies targeting pathophysiological mechanisms
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by
eosinophilic infiltration of the esophagus. It arises from a complex interplay of genetic …
eosinophilic infiltration of the esophagus. It arises from a complex interplay of genetic …
Breaking down the complex pathophysiology of eosinophilic esophagitis
B Underwood, TD Troutman, JT Schwartz - Annals of Allergy, Asthma & …, 2023 - Elsevier
Eosinophilic esophagitis (EoE) is a chronic and progressive immune-mediated disease of
the esophagus associated with antigen-driven type 2 inflammation and symptoms of …
the esophagus associated with antigen-driven type 2 inflammation and symptoms of …
[HTML][HTML] The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
Since the 1960 s, our health has been compromised by exposure to over 350,000 newly
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …