Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

The skin is the outermost layer of the body with an extensive surface area of approximately
1· 8 m2, and is the first line of defence against a multitude of external pathogens and …

The discovery of T cells resident in diverse tissues has altered our understanding of
adaptive immunity to encompass site-specific responses mediated by tissue-adapted …

Tissue-resident immune cells span both myeloid and lymphoid cell lineages, have been
found in multiple human tissues, and play integral roles at all stages of the immune …

Regionalized immune surveillance relies on the concerted efforts of diverse memory T cell
populations. Of these, tissue-resident memory T (TRM) cells are strategically positioned in …

Tissue-resident memory T cells (TRM) persist locally in nonlymphoid tissues where they
provide frontline defense against recurring insults. TRM at barrier surfaces express the …

Tissue resident memory T (TRM) cells reside in peripheral, non-lymphoid tissues such as
the skin, where they act as alarm-sensor cells or cytotoxic cells. Physiologically, skin TRM …

FOXP3+ regulatory T cells (Treg) play a critical role in mediating tolerance to self-antigens
and can repress antitumor immunity through multiple mechanisms. Therefore, targeted …

The skin contains a population of tissue-resident memory T cells (Trm) that is thought to
contribute to local tissue homeostasis and protection against environmental injuries …

Efficient immune responses against invading pathogens often involve coordination between
cells from both the innate and adaptive immune systems. For multiple decades, it has been …