Stem cell-derived islets (SC-islets) offer the potential to be an unlimited source of cells for
disease modeling and the treatment of diabetes. SC-islets can be genetically modified …

Diabetes mellitus (DM), a major global health concern, is a chronic metabolic disorder.
Bioactive compounds sourced from numerous marine natural products recently have drawn …

β‐Cell gene expression stress signatures in types 1 and 2 diabetes - PMC Skip to main content
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Pancreatic endocrine-exocrine crosstalk plays a key role in normal physiology and disease.
For instance, endocrine islet beta (β) cell secretion of insulin or cholecystokinin (CCK) …

Coxsackievirus B (CVB) infection has long been considered an environmental factor
precipitating Type 1 diabetes (T1D), an autoimmune disease marked by loss of insulin …

Abstract Type 2 diabetes (T2D) is a chronic condition where insulin-secreting pancreatic β-
cell mass and function is compromised. Etiology is traditionally linked to genetic …

Introduction Type 1 diabetic human islet β-cells are deficient in double C 2 like domain beta
(DOC2b) protein. Further, DOC2b protects against cytokine-induced pancreatic islet β-cell …