Structural and chemical biology of terpenoid cyclases

DW Christianson - Chemical reviews, 2017 - ACS Publications
The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Biosynthesis and biological functions of terpenoids in plants

D Tholl - Biotechnology of isoprenoids, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Terpenoids (isoprenoids) represent the largest
and most diverse class of chemicals among the myriad compounds produced by plants …

Terpene synthases as metabolic gatekeepers in the evolution of plant terpenoid chemical diversity

PS Karunanithi, P Zerbe - Frontiers in plant science, 2019 - frontiersin.org
Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

The draft genome of a diploid cotton Gossypium raimondii

K Wang, Z Wang, F Li, W Ye, J Wang, G Song, Z Yue… - Nature …, 2012 - nature.com
We have sequenced and assembled a draft genome of G. raimondii, whose progenitor is the
putative contributor of the D subgenome to the economically important fiber-producing …

The family of terpene synthases in plants: a mid‐size family of genes for specialized metabolism that is highly diversified throughout the kingdom

F Chen, D Tholl, J Bohlmann, E Pichersky - The Plant Journal, 2011 - Wiley Online Library
Some plant terpenes such as sterols and carotenes are part of primary metabolism and
found essentially in all plants. However, the majority of the terpenes found in plants are …

Bacterial terpene cyclases

JS Dickschat - Natural product reports, 2016 - pubs.rsc.org
Covering: up to 2015 This review summarises the accumulated knowledge about
characterised bacterial terpene cyclases. The structures of identified products and of …

Plant terpenes: defense responses, phylogenetic analysis, regulation and clinical applications

B Singh, RA Sharma - 3 Biotech, 2015 - Springer
The terpenoids constitute the largest class of natural products and many interesting products
are extensively applied in the industrial sector as flavors, fragrances, spices and are also …

Traversing the fungal terpenome

MB Quin, CM Flynn, C Schmidt-Dannert - Natural product reports, 2014 - pubs.rsc.org
Covering: 1965–2014 Fungi (Ascomycota and Basidiomycota) are prolific producers of
structurally diverse terpenoid compounds. Classes of terpenoids identified in fungi include …

Terpenoid synthase structures: a so far incomplete view of complex catalysis

Y Gao, RB Honzatko, RJ Peters - Natural product reports, 2012 - pubs.rsc.org
Covering: up to February 2012 The complexity of terpenoid natural products has drawn
significant interest, particularly since their common (poly) isoprenyl origins were discovered …

Induced‐fit mechanism in class I terpene cyclases

P Baer, P Rabe, K Fischer, CA Citron… - Angewandte Chemie …, 2014 - Wiley Online Library
We present crystallographic and functional data of selina‐4 (15), 7 (11)‐diene synthase
(SdS) from Streptomyces pristinaespiralis in its open and closed (ligand‐bound) …