Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an
individual's life and on society. Thus, develo** more effective therapeutic interventions is …

Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …

Dopamine (DA) is a major monoamine neurotransmitter in the brain and has essential roles
in higher functions of the brain. Malfunctions of dopaminergic signaling have been …

N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

There is a growing understanding that pathological genetic variation and environmental
insults during sensitive periods in brain development have long-term consequences on …

A growing body of evidence has emerged demonstrating a pathological link between
oxidative stress and schizophrenia. This evidence identifies oxidative stress as a …

N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

BackgroundAccumulating evidence shows that a propensity towards a pro-inflammatory
status in the brain plays an important role in schizophrenia. Anti-inflammatory drugs might …