The placebo effect: from concepts to genes

B Colagiuri, LA Schenk, MD Kessler, SG Dorsey… - Neuroscience, 2015 - Elsevier
Despite its initial treatment as a nuisance variable, the placebo effect is now recognized as a
powerful determinant of health across many different diseases and encounters. This is in …

Placebo effects: from the neurobiological paradigm to translational implications

F Benedetti - Neuron, 2014 - cell.com
Today we are witnessing a new science of placebo, a complex discipline that encompasses
several experimental approaches and translational implications. Modern neurobiological …

Serotonin synthesis and reuptake in social anxiety disorder: a positron emission tomography study

A Frick, F Åhs, J Engman, M Jonasson, I Alaie… - JAMA …, 2015 - jamanetwork.com
Importance Serotonin is involved in negative affect, but whether anxiety syndromes, such as
social anxiety disorder (SAD), are characterized by an overactive or underactive serotonin …

Neuroplasticity in response to cognitive behavior therapy for social anxiety disorder

KNT Månsson, A Salami, A Frick, P Carlbring… - Translational …, 2016 - nature.com
Patients with anxiety disorders exhibit excessive neural reactivity in the amygdala, which
can be normalized by effective treatment like cognitive behavior therapy (CBT). Mechanisms …

Thirty years of neuroscientific investigation of placebo and nocebo: the interesting, the good, and the bad

F Benedetti, E Frisaldi, A Shaibani - Annual Review of …, 2022 - annualreviews.org
Over the past 30 years there has been a surge of research on the placebo effect using a
neuroscientific approach. The interesting aspects of this effort are related to the identification …

Altered hippocampus and amygdala subregion connectome hierarchy in major depressive disorder

Y Jacob, LS Morris, G Verma, SB Rutter… - Translational …, 2022 - nature.com
The hippocampus and amygdala limbic structures are critical to the etiology of major
depressive disorder (MDD). However, there are no high-resolution characterizations of the …

Higher-and lower-order personality traits and cluster subtypes in social anxiety disorder

ME Costache, A Frick, K Månsson, J Engman, V Faria… - PloS one, 2020 - journals.plos.org
Social anxiety disorder (SAD) can come in different forms, presenting problems for
diagnostic classification. Here, we examined personality traits in a large sample of patients …

[HTML][HTML] Challenges of differential placebo effects in contemporary medicine: the example of brain stimulation

MJ Burke, TJ Kaptchuk, A Pascual-Leone - Annals of neurology, 2019 - ncbi.nlm.nih.gov
Abstract 'Differential placebo effects' is the concept that different types of placebos (eg inert
pill versus sham device) may yield different magnitudes of placebo effects. This issue has …

Understanding placebo and nocebo responses for pain management

L Colloca, C Grillon - Current pain and headache reports, 2014 - Springer
Placebo analgesia makes individuals experience relief of their pain simply by virtue of the
anticipation of a benefit. A reduction of pain can occur also when placebos follow the …

Altered neural correlates of affective processing after internet-delivered cognitive behavior therapy for social anxiety disorder

KNT Månsson, P Carlbring, A Frick, J Engman… - Psychiatry Research …, 2013 - Elsevier
Randomized controlled trials have yielded promising results for internet-delivered cognitive
behavior therapy (iCBT) for patients with social anxiety disorder (SAD). The present study …