Inhalation drug delivery in combating pulmonary infections: Advances and challenges

P Kumbhar, J Kaur, G De Rubis, KR Paudel… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …

Nanocrystals based pulmonary inhalation delivery system: Advance and challenge

P Yue, W Zhou, G Huang, F Lei, Y Chen, Z Ma… - Drug Delivery, 2022 - Taylor & Francis
Pulmonary inhalation administration is an ideal approach to locally treat lung disease and to
achieve systemic administration for other diseases. However, the complex nature of the …

Exploring the impact of morphology on the properties of biodegradable nanoparticles and their diffusion in complex biological medium

R Ridolfo, S Tavakoli, V Junnuthula… - …, 2020 - ACS Publications
Nanoparticle morphology (size, shape, and composition) and surface chemistry are the
determining factors underpinning the efficacy of such materials in therapeutic applications …

Extraction and characterization of nanocellulose crystals from cotton gin motes and cotton gin waste

JH Jordan, MW Easson, B Dien, S Thompson… - Cellulose, 2019 - Springer
Cellulose nanocrystals (CNC) have attracted a great deal of attention as an environmentally-
friendly biorenewable resource for use as reinforcing agents in nanocomposites, polymers …

Particle tracking of nanoparticles in soft matter

KA Rose, M Molaei, MJ Boyle, D Lee… - Journal of Applied …, 2020 - pubs.aip.org
Recent advances in optical microscopy instrumentation and processing techniques have led
to imaging that both breaks the diffraction barrier and enables sub-pixel resolution. This …

Rod-like mesoporous silica nanoparticles facilitate oral drug delivery via enhanced permeation and retention effect in mucus

W Liu, L Zhang, Z Dong, K Liu, H He, Y Lu, W Wu, J Qi - Nano Research, 2022 - Springer
The physiochemical characteristics of nanoparticles affect their in vitro and in vivo
performance significantly, such as diameter, surface chemistry, and shape. This paper …

Deep tissue penetration of bottle-brush polymers via cell capture evasion and fast diffusion

JM Rabanel, M Mirbagheri, M Olszewski, G **e… - ACS …, 2022 - ACS Publications
Drug nanocarriers (NCs) capable of crossing the vascular endothelium and deeply
penetrating into dense tissues of the CNS could potentially transform the management of …

Experimental and theoretical explorations of nanocarriers' multistep delivery performance for rational design and anticancer prediction

W Bao, F Tian, C Lyu, B Liu, B Li, L Zhang, X Liu… - Science …, 2021 - science.org
The poor understanding of the complex multistep process taken by nanocarriers during the
delivery process limits the delivery efficiencies and further hinders the translation of these …

Cellulose hydrolysis using ionic liquids and inorganic acids under dilute conditions: Morphological comparison of nanocellulose

JH Jordan, MW Easson, BD Condon - RSC advances, 2020 - pubs.rsc.org
The preparation of cellulose nanocrystals (CNCs) from cellulose extracted from cotton gin
motes (CGM) using an ionic liquid (1-butyl-3-methylimidazolium chloride,[BMIm] Cl) under …

Tadpole-Like Anisotropic Polymer/Lipid Janus Nanoparticles for Nose-to-Brain Drug Delivery: Importance of Geometry, Elasticity on Mucus-Penetration Ability

B Okmen Altas, GD Kalaycioglu… - Molecular …, 2024 - ACS Publications
Asymmetric geometry (aspect ratio> 1), moderate stiffness (ie, semielasticity), large surface
area, and low mucoadhesion of nanoparticles are the main features to reach the brain by …