Executive functions, or cognitive control, are higher-order cognitive functions needed for
adaptive goal-directed behaviours and are significantly impaired in majority of …

Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …

The inadequacy of a categorial approach to mental health diagnosis is now well-recognised,
with many authors, diagnostic manuals and funding bodies advocating a dimensional, trans …

A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

Uncertainty about a possible future threat disrupts our ability to avoid it or to mitigate its
negative impact and thus results in anxiety. Here, we focus the broad literature on the …

Over the course of a century, the meaning of interoception has changed from the restrictive
to the inclusive. In its inclusive sense, it bears relevance to every individual via its link to …

The medial prefrontal cortex (MPFC) has been posited to serve a variety of social, affective,
and cognitive functions. These conclusions have largely been driven by forward inference …

The prefrontal cortex (PFC), a cortical region that was once thought to be functionally
insignificant, is now known to play an essential role in the organization and control of goal …

Researchers have wondered how the brain creates emotions since the early days of
psychological science. With a surge of studies in affective neuroscience in recent decades …

Adolescence is characterized by making risky decisions. Early lesion and neuroimaging
studies in adults pointed to the ventromedial prefrontal cortex and related structures as …