Mathematical models for cell migration: a non-local perspective

L Chen, K Painter, C Surulescu… - … Transactions of the …, 2020 - royalsocietypublishing.org
We provide a review of recent advancements in non-local continuous models for migration,
mainly from the perspective of its involvement in embryonal development and cancer …

Biological modeling with nonlocal advection–diffusion equations

KJ Painter, T Hillen, JR Potts - Mathematical Models and Methods in …, 2024 - World Scientific
The employment of nonlocal PDE models to describe biological aggregation and other
phenomena has gained considerable traction in recent years. For cell populations, these …

Computational investigations of the and TGF- dynamics in a fibroblast cell

A Kothiya, N Adlakha - The European Physical Journal Plus, 2023 - Springer
Abstract Transforming growth factor-\(\beta\)(TGF-\(\beta\)) is a crucial regulator of fibroblast
cell function and is essential for maintaining and repairing connective tissues in the body …

Multiscale modelling of fibres dynamics and cell adhesion within moving boundary cancer invasion

R Shuttleworth, D Trucu - Bulletin of mathematical biology, 2019 - Springer
Recognised as one of the hallmarks of cancer, local cancer cell invasion is a complex
multiscale process that combines the secretion of matrix-degrading enzymes with a series of …

[HTML][HTML] Mathematical modelling of cancer invasion: Phenotypic transitioning provides insight into multifocal foci formation

Z Szymańska, M Lachowicz, N Sfakianakis… - Journal of …, 2024 - Elsevier
The transition from the epithelial to mesenchymal phenotype and its reverse (from
mesenchymal to epithelial) are crucial processes necessary for the progression and spread …

Mathematical models of cancer cell plasticity

HN Weerasinghe, PM Burrage, K Burrage… - Journal of …, 2019 - Wiley Online Library
Quantitative modelling is increasingly important in cancer research, hel** to integrate
myriad diverse experimental data into coherent pictures of the disease and able to …

Aggregation and travelling wave dynamics in a two-population model of cancer cell growth and invasion

V Bitsouni, D Trucu, MAJ Chaplain… - … Medicine and Biology …, 2018 - academic.oup.com
Cells adhere to each other and to the extracellular matrix (ECM) through protein molecules
on the surface of the cells. The breaking and forming of adhesive bonds, a process critical in …

The force of cell-cell adhesion in determining the outcome in a nonlocal advection diffusion model of wound healing.

G Webb - Mathematical Biosciences and Engineering, 2022 - go.gale.com
The movement of cells in spatial micro-environments can be modeled by continuous
variables for the continuum density of the cells. The partial differential equations of these …

Cell-scale degradation of peritumoural extracellular matrix fibre network and its role within tissue-scale cancer invasion

R Shuttleworth, D Trucu - Bulletin of Mathematical Biology, 2020 - Springer
Local cancer invasion of tissue is a complex, multiscale process which plays an essential
role in tumour progression. During the complex interaction between cancer cell population …

Nonlocal adhesion models for microorganisms on bounded domains

T Hillen, A Buttenschön - SIAM Journal on Applied Mathematics, 2020 - SIAM
In 2006 Armstrong, Painter, and Sherratt formulated a nonlocal differential equation model
for cell-cell adhesion. For the one-dimensional case on a bounded domain we derive …