BACKGROUND The human brain contains about 100 billion neurons, each of which makes
thousands of synaptic connections. Although individual neurons can themselves be …

Fully automatic deep learning has become the state-of-the-art technique for many tasks
including image acquisition, analysis and interpretation, and for the extraction of clinically …

Connections between neurons can be mapped by acquiring and analysing electron
microscopic brain images. In recent years, this approach has been applied to chunks of …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

Abstract Systems neuroscience seeks explanations for how the brain implements a wide
variety of perceptual, cognitive and motor tasks. Conversely, artificial intelligence attempts to …

Neurons have diverse molecular, morphological, connectional and functional properties. We
believe that the only realistic way to manage this complexity—and thereby pave the way for …

The vertebrate retina first evolved some 500 million years ago in ancestral marine
chordates. Since then, the eyes of different species have been tuned to best support their …

Moral intuitions are a central motivator in human behavior. Recent work highlights the
importance of moral intuitions for understanding a wide range of issues ranging from online …

Patterns of gene expression can be used to characterize and classify neuronal types. It is
challenging, however, to generate taxonomies that fulfill the essential criteria of being …