Update οn the diagnosis and management of systemic lupus erythematosus

A Fanouriakis, N Tziolos, G Bertsias… - Annals of the rheumatic …, 2021 - ard.bmj.com
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

Lupus nephritis

HJ Anders, R Saxena, M Zhao, I Parodis… - Nature reviews Disease …, 2020 - nature.com
Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe
organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most …

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus

A Fanouriakis, M Kostopoulou, A Alunno… - Annals of the …, 2019 - ard.bmj.com
Our objective was to update the EULAR recommendations for the management of systemic
lupus erythematosus (SLE), based on emerging new evidence. We performed a systematic …

2021 DORIS definition of remission in SLE: final recommendations from an international task force

RF van Vollenhoven, G Bertsias, A Doria… - Lupus science & …, 2021 - lupus.bmj.com
Objective To achieve consensus on a definition of remission in SLE (DORIS). Background
Remission is the stated goal for both patient and caregiver, but consensus on a definition of …

Novel paradigms in systemic lupus erythematosus

T Dörner, R Furie - The Lancet, 2019 - thelancet.com
The heterogeneity of systemic lupus erythematosus (SLE), long recognised by clinicians, is
now challenging the entire lupus community, from geneticists to clinical investigators …

Management strategies and future directions for systemic lupus erythematosus in adults

L Durcan, T O'Dwyer, M Petri - The Lancet, 2019 - thelancet.com
Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of
self-tolerance and formation of nuclear autoantigens and immune complexes resulting in …

Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with …

A Mathian, M Mahevas, J Rohmer… - Annals of the …, 2020 - ard.bmj.com
The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
disease 2019 (COVID-19) represents a source of concern for the management of patients …

Treat-to-target in systemic lupus erythematosus: advancing towards its implementation

AR Parra Sánchez, AE Voskuyl… - Nature reviews …, 2022 - nature.com
The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial

J He, R Zhang, M Shao, X Zhao, M Miao… - Annals of the …, 2020 - ard.bmj.com
Objectives Open-labelled clinical trials suggested that low-dose IL-2 might be effective in
treatment of systemic lupus erythematosus (SLE). A double-blind and placebo-controlled …

[HTML][HTML] An expert consensus framework for asthma remission as a treatment goal

A Menzies-Gow, M Bafadhel, WW Busse… - Journal of Allergy and …, 2020 - Elsevier
With novel therapies in development, there is an opportunity to consider asthma remission
as a treatment goal. In this Rostrum, we present a generalized framework for clinical and …