Recent advances in the use of SPME for drug analysis in clinical, toxicological, and forensic medicine studies

D Leszczyńska, A Hallmann, N Treder, T Bączek… - Talanta, 2024 - Elsevier
Solid-phase microextraction (SPME) has gained attention as a simple, fast, and non-
exhaustive extraction technique, as its unique features enable its use for the extraction of …

[HTML][HTML] Managing the coagulopathy associated with cardiopulmonary bypass

J Bartoszko, K Karkouti - Journal of Thrombosis and Haemostasis, 2021 - Elsevier
Cardiopulmonary bypass (CPB) has allowed for significant surgical advancements, but
accompanying risks can be significant and must be expertly managed. One of the foremost …

Thin film microextraction: Towards faster and more sensitive microextraction

YA Olcer, M Tascon, AE Eroglu, E Boyacı - TrAC Trends in Analytical …, 2019 - Elsevier
Thin film microextraction (TFME) is an analytical tool that has been proven to be suitable for
integrated sampling and sample preparation of a wide variety of routine and on-site …

Tranexamic acid for the prevention and treatment of bleeding in surgery, trauma and bleeding disorders: a narrative review

A Ockerman, T Vanassche, M Garip, C Vandenbriele… - Thrombosis …, 2021 - Springer
Objectives We review the evidence for tranexamic acid (TXA) for the treatment and
prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight …

Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients

J Poeran, JJ Chan, N Zubizarreta, M Mazumdar… - …, 2021 - ingentaconnect.com
Background: With increasing use of tranexamic acid in total hip and knee arthroplasties,
safety concerns remain. Using national claims data, this study examined tranexamic acid …

[HTML][HTML] Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

L Chen, Y Zhang, YX Zhang, WL Wang, DM Sun… - Journal of …, 2024 - Elsevier
Tyrosine kinase inhibitors (TKIs) have emerged as the first-line small molecule drugs in
many cancer therapies, exerting their effects by impeding aberrant cell growth and …

Update on applications and limitations of perioperative tranexamic acid

PA Patel, JA Wyrobek, AJ Butwick… - Anesthesia & …, 2022 - journals.lww.com
Tranexamic acid (TXA) is a potent antifibrinolytic with documented efficacy in reducing blood
loss and allogeneic red blood cell transfusion in several clinical settings. With a growing …

Exposure-response relationship of tranexamic acid in cardiac surgery.

PJ Zufferey, J Lanoiselee, B Graouch, B Vieille… - …, 2021 - europepmc.org
Background It is unclear whether high-dose regimens of tranexamic acid in cardiac surgery
(total dose, 80 to 100 mg/kg) confer a clinical advantage over low-dose regimens (total dose …

Tranexamic acid: current use in obstetrics, major orthopedic, and trauma surgery

J Wong, RB George, CM Hanley, C Saliba… - Canadian Journal of …, 2021 - Springer
Abstract Purpose In this Continuing Professional Development module, we review the
practical pharmacology of tranexamic acid and its clinical use in trauma, obstetrics, and …

Trace-level monitoring of anti-cancer drug residues in wastewater and biological samples by thin-film solid-phase micro-extraction using electrospun polyfam/Co-MOF …

P Khodayari, N Jalilian, H Ebrahimzadeh… - … of Chromatography A, 2021 - Elsevier
Sample preparation methods with high accuracy and matrix resistance will benefit the quick
analysis of desired analytes in an intricate matrix, such as the monitoring of drug samples in …