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TCR-engineered T cells directed against Ropporin-1 constitute a safe and effective treatment for triple-negative breast cancer
D Kortleve, D Hammerl, M van Brakel, R Wijers… - Cancer …, 2024 - aacrjournals.org
Triple-negative breast cancer (TNBC) has an urgent need for new therapies. We discovered
Ropporin-1 (ROPN1) as a target to treat TNBC with T cells. ROPN1 showed high and …
Ropporin-1 (ROPN1) as a target to treat TNBC with T cells. ROPN1 showed high and …
Retroviral Transduction of Human Primary T Cells Followed by Real-Time T-Cell-Mediated Cancer Cell Cytolysis Analysis
A Rahbech, R Debets, P thor Straten… - … : Methods and Protocols, 2023 - Springer
Retroviral transduction is a highly useful tool to genetically engineer hard-to-transfect human
primary cells. Here, we transduce human primary T cells with a tumor-specific T cell …
primary cells. Here, we transduce human primary T cells with a tumor-specific T cell …