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Physical properties of the bacterial outer membrane
J Sun, ST Rutherford, TJ Silhavy… - Nature Reviews …, 2022 - nature.com
It has long been appreciated that the Gram-negative outer membrane acts as a permeability
barrier, but recent studies have uncovered a more expansive and versatile role for the outer …
barrier, but recent studies have uncovered a more expansive and versatile role for the outer …
Regulation of peptidoglycan synthesis and remodelling
AJF Egan, J Errington, W Vollmer - Nature Reviews Microbiology, 2020 - nature.com
Bacteria surround their cell membrane with a net-like peptidoglycan layer, called sacculus,
to protect the cell from bursting and maintain its cell shape. Sacculus growth during …
to protect the cell from bursting and maintain its cell shape. Sacculus growth during …
Growth and division of the peptidoglycan matrix
PDA Rohs, TG Bernhardt - Annual review of microbiology, 2021 - annualreviews.org
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
The bacterial cell wall: from lipid II flip** to polymerization
The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
Peptidoglycan maturation controls outer membrane protein assembly
G Mamou, F Corona, R Cohen-Khait, NG Housden… - Nature, 2022 - nature.com
Linkages between the outer membrane of Gram-negative bacteria and the peptidoglycan
layer are crucial for the maintenance of cellular integrity and enable survival in challenging …
layer are crucial for the maintenance of cellular integrity and enable survival in challenging …
Splitsville: structural and functional insights into the dynamic bacterial Z ring
DP Haeusser, W Margolin - Nature Reviews Microbiology, 2016 - nature.com
Bacteria must divide to increase in number and colonize their niche. Binary fission is the
most widespread means of bacterial cell division, but even this relatively simple mechanism …
most widespread means of bacterial cell division, but even this relatively simple mechanism …
Peptidoglycan: structure, synthesis, and regulation
S Garde, PK Chodisetti, M Reddy - EcoSal Plus, 2021 - journals.asm.org
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
Cell-wall recycling of the gram-negative bacteria and the nexus to antibiotic resistance
DA Dik, JF Fisher, S Mobashery - Chemical reviews, 2018 - ACS Publications
The importance of the cell wall to the viability of the bacterium is underscored by the breadth
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …
Polymyxin: alternative mechanisms of action and resistance
MJ Trimble, P Mlynárčik… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Antibiotic resistance among pathogenic bacteria is an ever-increasing issue worldwide.
Unfortunately, very little has been achieved in the pharmaceutical industry to combat this …
Unfortunately, very little has been achieved in the pharmaceutical industry to combat this …
Antimicrobial activity of cationic antimicrobial peptides against gram-positives: current progress made in understanding the mode of action and the response of …
Antimicrobial peptides (AMPs) have been proposed as a novel class of antimicrobials that
could aid the fight against antibiotic resistant bacteria. The mode of action of AMPs as acting …
could aid the fight against antibiotic resistant bacteria. The mode of action of AMPs as acting …