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Measuring cerebrovascular reactivity: what stimulus to use?
J Fierstra, O Sobczyk… - The Journal of …, 2013 - Wiley Online Library
Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …
The right ventricle in ARDS
ARDS is associated with poor clinical outcomes, with a pooled mortality rate of
approximately 40% despite best standards of care. Current therapeutic strategies are based …
approximately 40% despite best standards of care. Current therapeutic strategies are based …
Targeted therapeutic mild hypercapnia after cardiac arrest: a phase II multi-centre randomised controlled trial (the CCC trial)
GM Eastwood, AG Schneider, S Suzuki, L Peck… - Resuscitation, 2016 - Elsevier
Background In intensive care observational studies, hypercapnia after cardiac arrest (CA) is
independently associated with improved neurological outcome. However, the safety and …
independently associated with improved neurological outcome. However, the safety and …
CO2 Blood Oxygen Level–dependent MR Map** of Cerebrovascular Reserve in a Clinical Population: Safety, Tolerability, and Technical Feasibility
VR Spano, DM Mandell, J Poublanc, K Sam… - Radiology, 2013 - pubs.rsna.org
Purpose To evaluate the safety, tolerability, and technical feasibility of map**
cerebrovascular reactivity (CVR) in a clinical population by using a precise prospectively …
cerebrovascular reactivity (CVR) in a clinical population by using a precise prospectively …
Glucose control in the ICU—how tight is too tight?
SE Inzucchi, MD Siegel - New England Journal of Medicine, 2009 - Mass Medical Soc
For the past decade, hospitals have focused on the inpatient management of hyperglycemia,
particularly in the intensive care unit (ICU). Extensive observational data have shown a …
particularly in the intensive care unit (ICU). Extensive observational data have shown a …
Systemic inflammation impairs respiratory chemoreflexes and plasticity
AG Huxtable, S Vinit, JA Windelborn, SM Crader… - Respiratory physiology …, 2011 - Elsevier
Many lung and central nervous system disorders require robust and appropriate
physiological responses to assure adequate breathing. Factors undermining the efficacy of …
physiological responses to assure adequate breathing. Factors undermining the efficacy of …
A review of the use of transnasal humidified rapid insufflation ventilatory exchange for patients undergoing surgery in the shared airway setting
L Huang, N Dharmawardana, A Badenoch, EH Ooi - Journal of anesthesia, 2020 - Springer
Transnasal humidified rapid insufflation ventilatory exchange (THRIVE) is a recent
technique that delivers warm humidified high flow oxygen to patients, allowing for prolonged …
technique that delivers warm humidified high flow oxygen to patients, allowing for prolonged …
Association of hypercapnia and hypercapnic acidosis with clinical outcomes in mechanically ventilated patients with cerebral injury
R Tiruvoipati, D Pilcher, J Botha, H Buscher… - JAMA …, 2018 - jamanetwork.com
Importance Clinical studies investigating the effects of hypercapnia and hypercapnic
acidosis in acute cerebral injury are limited. The studies performed so far have mainly …
acidosis in acute cerebral injury are limited. The studies performed so far have mainly …
Low-flow CO2removal integrated into a renal-replacement circuit can reduce acidosis and decrease vasopressor requirements
C Forster, J Schriewer, S John, KU Eckardt, C Willam - Critical Care, 2013 - Springer
Introduction Lung-protective ventilation in patients with ARDS and multiorgan failure,
including renal failure, is often paralleled with a combined respiratory and metabolic …
including renal failure, is often paralleled with a combined respiratory and metabolic …
Low tidal volume ventilation in patients without acute respiratory distress syndrome: a paradigm shift in mechanical ventilation
J Lipes, A Bojmehrani… - Critical care research and …, 2012 - Wiley Online Library
Protective ventilation with low tidal volume has been shown to reduce morbidity and
mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress …
mortality in patients suffering from acute lung injury (ALI) and acute respiratory distress …