Electrochemical SARS-CoV-2 sensing at point-of-care and artificial intelligence for intelligent COVID-19 management
To manage the COVID-19 pandemic, development of rapid, selective, sensitive diagnostic
systems for early stage β-coronavirus severe acute respiratory syndrome (SARS-CoV-2) …
systems for early stage β-coronavirus severe acute respiratory syndrome (SARS-CoV-2) …
COVID-19 vaccine: where are we now and where should we go?
Introduction The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has
currently caused the pandemic with a high progressive speed and has been considered as …
currently caused the pandemic with a high progressive speed and has been considered as …
Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …
burden to the global society and is accompanied by various evolution of the virus genome …
Potential SARS-CoV-2 main protease inhibitors
Highlights•The SARS-CoV-2 main protease is a prime drug target.•Coronavirus main
proteases share a structurally conserved substrate-binding region.•The structure and …
proteases share a structurally conserved substrate-binding region.•The structure and …
Small molecules in the treatment of COVID-19
S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
societies and economies. Until now, effective therapeutics against COVID-19 are in high …
Key interacting residues between RBD of SARS-CoV-2 and ACE2 receptor: combination of molecular dynamics simulation and density functional calculation
The spike protein of SARS-CoV-2 binds to the ACE2 receptor via its receptor-binding
domain (RBD), with the RBD–ACE2 complex presenting an essential molecular target for …
domain (RBD), with the RBD–ACE2 complex presenting an essential molecular target for …
Rapidly determining the 3D structure of proteins by surface-enhanced Raman spectroscopy
Despite great advances in protein structure analysis, label-free and ultrasensitive methods
to obtain the natural and dynamic three-dimensional (3D) structures are still urgently …
to obtain the natural and dynamic three-dimensional (3D) structures are still urgently …
Ultrasensitive and reusable graphene oxide-modified double-interdigitated capacitive (DIDC) sensing chip for detecting SARS-CoV-2
This research reveals the promising functionalization of graphene oxide (GrO)-glazed
double-interdigitated capacitive (DIDC) biosensing platform to detect severe acute …
double-interdigitated capacitive (DIDC) biosensing platform to detect severe acute …
Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
Screening of plant-based natural compounds as a potential COVID-19 main protease inhibitor: an in silico docking and molecular dynamics simulation approach
A new strain of coronavirus (CoV) has been identified as SARS-CoV-2, which is responsible
for the recent COVID-19 pandemic. Currently, there is no approved vaccine or drug …
for the recent COVID-19 pandemic. Currently, there is no approved vaccine or drug …